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1. (WO2005085260) PYRROLOBENZODIAZEPINES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2005/085260 International Application No.: PCT/GB2005/000915
Publication Date: 15.09.2005 International Filing Date: 09.03.2005
IPC:
C07D 519/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
519
Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/ or C07D455/257
Applicants:
SPIROGEN LIMITED [GB/GB]; 79 George Street Ryde Isle of Wight PO33 2JF, GB (AllExceptUS)
HOWARD, Philip Wilson [GB/GB]; GB (UsOnly)
GREGSON, Stephen, John [GB/GB]; GB (UsOnly)
TAYLOR, Peter William [GB/GB]; GB (UsOnly)
THURSTON, David Edwin [GB/GB]; GB (UsOnly)
HADJIVASSILEVA, Tsveta Stepanova [BG/GB]; GB (UsOnly)
Inventors:
HOWARD, Philip Wilson; GB
GREGSON, Stephen, John; GB
TAYLOR, Peter William; GB
THURSTON, David Edwin; GB
HADJIVASSILEVA, Tsveta Stepanova; GB
Agent:
WATSON, Robert ; Mewburn Ellis LLP York House 23 Kingsway London Greater London WC2B 6HP, GB
Priority Data:
0405319.509.03.2004GB
0412409.503.06.2004GB
Title (EN) PYRROLOBENZODIAZEPINES
(FR) PYRROLOBENZODIAZEPINES
Abstract:
(EN) A compound of formula (I) and salts and solvates thereof, wherein: R10 is a nitrogen protecting group and R11 is either OH or O-R12, wherein R12 is an oxygen protecting group, or R10 and R11 together form a double bond between N10 and C11; and R10' and R11' are selected from the same options as R10 and R11 respectively.
(FR) L'invention concerne un composé représenté par la formule (I). Elle concerne également des sels et des solvates de ce composé. Dans cette formule R10 représente un groupe protecteur d'azote et R11 représente soit OH soit O-R12, R12 consistant en un groupe protecteur d'oxygène, ou R10 et R11 forment ensemble une liaison double entre N10 et C11; et R10' et R11' sont choisis parmi les mêmes options que respectivement R10 et R11.
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Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP1723152JP2007528383US20070185073