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1. WO2005069844 - IMPROVING PROFILES OF LIPID PROTEINS AND INHIBITING HMG-CoA REDUCTASE

Publication Number WO/2005/069844
Publication Date 04.08.2005
International Application No. PCT/US2005/001158
International Filing Date 14.01.2005
Chapter 2 Demand Filed 15.11.2005
IPC
A61K 36/746 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
74Rubiaceae (Madder family)
746Morinda
CPC
A61K 36/746
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
74Rubiaceae (Madder family)
746Morinda
A61P 3/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
06Antihyperlipidemics
Applicants
  • PALU, Afa, Kehaati [US]/[US]
  • JENSEN, Claude, Jarakae [US]/[US]
  • WANG, Mian, Ying, [US]/[US]
  • ZHOU, Bing-Nan [US]/[US]
  • STORY, Stephen [US]/[US]
Inventors
  • PALU, Afa, Kehaati
  • JENSEN, Claude, Jarakae
  • WANG, Mian, Ying,
  • ZHOU, Bing-Nan
  • STORY, Stephen
Agents
  • KRIEGER, Michael, F.
Priority Data
11/034,50513.01.2005US
60/536,66315.01.2004US
60/552,14410.03.2004US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) IMPROVING PROFILES OF LIPID PROTEINS AND INHIBITING HMG-CoA REDUCTASE
(FR) AMELIORATION DE PROFILS DE PROTEINES LIPIDIQUES ET INHIBITION DE HMG-COA REDUCTASE
Abstract
(EN)
The present invention comprises methods and compositions for improving profiles of lipid proteins, reducing low-density lipoprotein levels, increasing high-density lipoprotein levels, decreasing the absorption of fatty acids across the intestinal epithelium and inhibiting HMG-CoA Reductase in living organisms utilizing Morinda citrifolia L activity in mammals, including humans.
(FR)
La présente invention concerne des méthodes et des compositions permettant d'améliorer les profils de protéines lipidiques, de réduire les niveaux de lipoprotéines haute densité, de diminuer l'absorption d'acides gras à travers l'épithélium intestinal et d'inhiber la HMG-CoA réductase dans des organismes vivants par utilisation de l'activité de Morinda citrifolia L chez des mammifères, notamment chez les humains.
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