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1. (WO2005068612) HUMAN HEPATIC PROGENITOR CELLS AND METHODS OF USE THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/068612    International Application No.:    PCT/IB2005/000660
Publication Date: 28.07.2005 International Filing Date: 14.01.2005
IPC:
A61K 35/407 (2006.01), A61P 1/16 (2006.01), C12N 5/074 (2010.01), C12Q 1/02 (2006.01), G01N 33/50 (2006.01), A61K 35/12 (2006.01)
Applicants: NOVAHEP AB [SE/SE]; Drottninggatan 33, Box 7710, S-103 95 Stockholm (SE) (For All Designated States Except US).
HOLGERSSON, Suchitra [SE/SE]; (SE) (For US Only)
Inventors: HOLGERSSON, Suchitra; (SE)
Agent: CRUMP, Julian Richard John; Mintz Levin Cohn Ferris Glovsky & Popeo, Intellectual Property LLP, The Rectory, 9 Ironmonger Lane, London EC2V 8EY (GB)
Priority Data:
60/536,405 14.01.2004 US
60/623,003 27.10.2004 US
Title (EN) HUMAN HEPATIC PROGENITOR CELLS AND METHODS OF USE THEREOF
(FR) CELLULES PROGENITRICES HEPATIQUES HUMAINES ET PROCEDES D'UTILISATION CORRESPONDANTS
Abstract: front page image
(EN)Liver progenitor cells immunoreactive for CD117, as well as for CD34 capable of proliferating in a culture; and differentiating in vivo into a hepatocyte, a cholangiocyte or a sinusoidal cell are provided. The cultures can be expended over a large number of passages and integrate well after transplantation into adult liver.
(FR)L'invention concerne des cellules progénitrices immunoréactives du foie à CD117, ainsi qu'à CD34 capables de proliférer dans une culture et de se différentier in vivo en cellules hépatocytes, cholangiocytes ou sinusoïdales. Les cultures peuvent être étalées sur un nombre élevé de passages et bien s'intégrer après la transplantation dans un foie adulte.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)