WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2005068456) PRODUCTION METHOD
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2005/068456 International Application No.: PCT/EP2004/014870
Publication Date: 28.07.2005 International Filing Date: 31.12.2004
IPC:
C07D 409/14 (2006.01)
Applicants: BERWE, Mathias[DE/DE]; DE (UsOnly)
THOMAS, Christian[DE/DE]; DE (UsOnly)
REHSE, Joachim[DE/DE]; DE (UsOnly)
GROTJOHANN, Dirk[DE/DE]; DE (UsOnly)
BAYER HEALTHCARE AG[DE/DE]; 51368 Leverkusen, DE (AllExceptUS)
Inventors: BERWE, Mathias; DE
THOMAS, Christian; DE
REHSE, Joachim; DE
GROTJOHANN, Dirk; DE
Common
Representative:
BAYER HEALTHCARE AG; Law and Patents, Patents and Licensing 51368 Leverkusen, DE
Priority Data:
102004002044.215.01.2004DE
Title (EN) PRODUCTION METHOD
(FR) PROCEDE DE PREPARATION
(DE) HERSTELLVERFAHREN
Abstract:
(EN) The invention relates to a method for producing 5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidine-5-yl}-methyl)-2-thiophene carboxamide from 2-[(2S)-2-oxiranylmethyl]-1H-isoindol-1,3(2H)-dione, 4-(4-aminophenyl)-3-morpholinone, and 5-chlorothiophene-2-carbonyl chloride.
(FR) La présente invention concerne un procédé pour préparer du 5-chlore-<i>N</i>-({(5<i>S</i>)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phényl]-1,3-oxazolidin-5-yl}-méthyl)-2-thiophène carboxamide à partir de 2-[(2<i>S</i>)-2-oxiranylméthyl]-1<i>H</i>-isoindol-1,3(2<i>H</i>)-dione, de 4-(4-aminophényl)-3-morpholinone et de chlorure de 5-chlorthiophène-2-carbonyl.
(DE) Die vorliegende Erfindung betrifft ein Verfahren zur Herstellung von 5-Chlor-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophencarboxamid ausgehend von 2-[(2S)-2-Oxiranylmethyl]-1H-isoindol-1,3(2H)-dion, 4-(4-Aminophenyl)-3-morpholinon und 5-Chlorthiophen-2-carbonylchlorid.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: German (DE)
Filing Language: German (DE)