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1. (WO2005067983) IMPROVED GASTRIN RELEASING PEPTIDE COMPOUNDS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2005/067983 International Application No.: PCT/US2004/022115
Publication Date: 28.07.2005 International Filing Date: 12.07.2004
Chapter 2 Demand Filed: 06.07.2005
IPC:
A61K 51/00 (2006.01) ,A61M 36/14 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
51
Preparations containing radioactive substances for use in therapy or testing in vivo
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
M
DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
36
Applying radioactive material to the body
14
Radioactive dressings
Applicants: CAPPELLETTI, Enrico[IT/IT]; IT (UsOnly)
LATTUADA, Luciano[IT/IT]; IT (UsOnly)
LINDER, Karen, E.[US/US]; US (UsOnly)
MARINELLI, Edmund, R.[US/US]; US (UsOnly)
NANJAPPAN, Palaniappa[US/US]; US (UsOnly)
RAJU, Natarajan[US/US]; US (UsOnly)
SWENSON, Rolf, E.[US/US]; US (UsOnly)
TWEEDLE,Michael[US/US]; US (UsOnly)
RAMALINGAM, Kondareddiar[US/US]; US (UsOnly)
BRACCO IMAGING S.P.A.[IT/IT]; Via Egidio Folli 50 I-20134 Milan, IT (AllExceptUS)
Inventors: CAPPELLETTI, Enrico; IT
LATTUADA, Luciano; IT
LINDER, Karen, E.; US
MARINELLI, Edmund, R.; US
NANJAPPAN, Palaniappa; US
RAJU, Natarajan; US
SWENSON, Rolf, E.; US
TWEEDLE,Michael; US
RAMALINGAM, Kondareddiar; US
Agent: RHOADS, Donald; Kramer Levin Naftalis & Frankel LLP 919 Third Avenue New York, NY 10022, US
Priority Data:
10/828,92520.04.2004US
PCT/US03/4132824.12.2003US
Title (EN) IMPROVED GASTRIN RELEASING PEPTIDE COMPOUNDS
(FR) COMPOSÉS PEPTIDIQUES DE LIBÉRATION DE GASTRINE AMÉLIORÉS
Abstract:
(EN) New and improved compounds for use in diagnostic imaging or therapy having the formula M-N-O-P-G, wherein M is an optical label or a metal chelator (in the form complexed with a metal radionuclide or not), N-O-P is the linker, and G is the GRP receptor targeting peptide. Methods for imaging a patient and/or providing radiotherapy or phototherapy to a patient using the compounds of the invention are also provided. Methods and kits for preparing a diagnostic imaging agent from the compound is further provided. Methods and kits for preparing a radiotherapeutic agent are further provided.
(FR) La présente invention a trait à des nouveaux composés améliorés destinés à être utilisés dans l'imagerie diagnostique ou en thérapie représentés par la formule M-N-O-P-G, dans laquelle M est une étiquette optique ou un chélateur métallique (sous la forme d'un complexe avec ou sans radionucléide métallique), N-O-P est le lieur, et G est le peptide de ciblage du récepteur GRP. L'invention a également trait à des procédés d'imagerie d'un patient et/ou pour administrer une radiothérapie ou photothérapie à un patient au moyen des composés de l'invention. L'invention a trait en outre à des procédés et des trousses pour la préparation d'un agent d'imagerie diagnostique à partir du composé. Enfin, l'invention a trait à des procédés et des trousses pour la préparation d'un agent radiothérapeutique.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)