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1. WO2005067902 - NOVEL COMPOSITIONS COMPRISING HIGHER PRIMARY ALCOHOLS AND NICOTINIC ACID AND PROCESS OF PREPARATION THEREOF

Publication Number WO/2005/067902
Publication Date 28.07.2005
International Application No. PCT/IN2005/000023
International Filing Date 19.01.2005
IPC
A61K 31/045 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
A61K 31/455 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
44Non-condensed pyridines; Hydrogenated derivatives thereof
455Nicotinic acid, i.e. niacin; Derivatives thereof, e.g. esters, amides
CPC
A61K 31/045
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
A61K 31/455
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
44Non condensed pyridines; Hydrogenated derivatives thereof
455Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
A61P 3/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
06Antihyperlipidemics
Applicants
  • PANACEA BIOTEC LTD., [IN]/[IN] (AllExceptUS)
  • JAIN, Rajesh [IN]/[IN] (UsOnly)
  • JINDAL, Kour, Chand (UsOnly)
  • SINGH, Sukhjeet (UsOnly)
Inventors
  • JAIN, Rajesh
  • JINDAL, Kour, Chand
  • SINGH, Sukhjeet
Agents
  • GUPTA, Bhartee
Priority Data
101/DEL/200420.01.2004IN
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) NOVEL COMPOSITIONS COMPRISING HIGHER PRIMARY ALCOHOLS AND NICOTINIC ACID AND PROCESS OF PREPARATION THEREOF
(FR) NOUVELLES COMPOSITIONS COMPRENANT DES ALCOOLS PRIMAIRES SUPERIEURS ET DE L'ACIDE NICOTINIQUE ET PROCEDE DE PREPARATION CORRESPONDANT
Abstract
(EN) A composition comprising a mixture of higher primary aliphatic alcohols from 24 to 39 carbon atoms; at least one another component selected from resins and pigments, hydrocarbons, esters, ketones and aldehydes, and phenolic compounds, and nicotinic acid, its salts or derivatives thereof optionally with excipients, and process of preparation of such composition is provided. Also provided are method of treatment and use of such composition for reducing abnormal lipid parameters associated with hyperlipidemia. The compositions of the present invention are useful pharmaceutically or as a dietary supplement.
(FR) La présente invention concerne une composition comprenant un mélange d'alcools aliphatiques supérieurs contenant de 24 à 39 atomes de carbones; au moins un autre composant choisi parmi les résines et les pigments, les hydrocarbures, les esters, les cétones et les aldéhydes, et des composés phénoliques, et de l'acide nicotinique, leurs sels ou des dérivés de ceux-ci, éventuellement avec des excipients. La présente invention concerne également un procédé permettant de préparer une telle composition. Cette invention concerne également une méthode thérapeutique consistant à utiliser une telle composition pour réduire les paramètres lipidiques anormaux associés à l'hyperlipidémie. Les compositions décrites dans cette invention sont utiles sur le plan pharmaceutique ou en tant que complément alimentaire.
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