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1. (WO2005066357) METHOD OF SCREENING MOLECULE ASSOCIATED WITH PSYCHIATRIC DISORDER
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/066357    International Application No.:    PCT/JP2005/000009
Publication Date: 21.07.2005 International Filing Date: 05.01.2005
IPC:
A61K 45/00 (2006.01), A61P 25/18 (2006.01), A61P 25/30 (2006.01), A61P 43/00 (2006.01), C12N 15/09 (2006.01), C12Q 1/02 (2006.01), G01N 33/15 (2006.01), G01N 33/50 (2006.01)
Applicants: MITSUBISHI PHARMA CORPORATION [JP/JP]; 6-9, Hiranomachi 2-chome, Chuo-ku, Osaka-shi Osaka 5410046 (JP) (For All Designated States Except US).
NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY [JP/JP]; 1, Furo-cho, Chikusa-ku, Nagoya-shi, Aichi 4648601 (JP) (For All Designated States Except US).
MORI, Ikue [JP/JP]; (JP) (For US Only).
KAJII, Yasushi [JP/JP]; (JP) (For US Only)
Inventors: MORI, Ikue; (JP).
KAJII, Yasushi; (JP)
Agent: SIKs & Co.; 8th Floor, Kyobashi-Nisshoku Bldg., 8-7, Kyobashi 1-chome, Chuo-ku, Tokyo 1040031 (JP)
Priority Data:
2004-000179 05.01.2004 JP
Title (EN) METHOD OF SCREENING MOLECULE ASSOCIATED WITH PSYCHIATRIC DISORDER
(FR) METHODE DE CRIBLAGE D'UNE MOLECULE ASSOCIEE A UN TROUBLE PSYCHIATRIQUE
(JA) 精神疾患関連分子のスクリーニング方法
Abstract: front page image
(EN)A method of screening genes associated with psychiatric disorders such as schizophrenia, comprising the step of with the use of nematode worm under behavioral sensitization with amphetamine, methamphetamine, apomorphine, cocaine or the like, screening genes associated with the behavioral sensitization. Further, there is provided a method of screening a substance effective in the prevention and/or treatment of psychiatric disorders, comprising the step of with the use of nematode worm under behavioral sensitization with amphetamine, methamphetamine, apomorphine, cocaine or the like, screening a substance influencing the behavioral sensitization.
(FR)L'invention concerne une méthode de criblage de gènes associés à des troubles psychiatriques, tels que la schizophrénie, qui consiste à utiliser un ver nématode sous sensibilisation comportementale par amphétamine, méthamphétamine, apomorphine, cocaïne ou analogue, pour cribler des gènes associés à la sensibilisation comportementale. L'invention concerne en outre une méthode de criblage d'une substance efficace dans la prévention et/ou le traitement de troubles psychiatriques, qui consiste à utiliser un ver nématode sous sensibilisation comportementale par amphétamine, méthamphétamine, apomorphine, cocaïne ou analogue, pour cribler une substance influant sur la sensibilisation comportementale.
(JA) 統合失調症などの精神疾患に関連する遺伝子をスクリーニングする方法であって、アンフェタミン、メタンフェタミン、アポモルフィン、又はコカインなどで行動感作した線虫を用いて該行動感作に関連する遺伝子をスクリーニングする工程を含む方法、及び精神疾患の予防及び/又は治療のために有用な物質のスクリーニング方法であって、アンフェタミン、メタンフェタミン、アポモルフィン、又はコカインなどで行動感作した線虫を用いて該行動感作に影響を与える物質をスクリーニングする工程を含む方法。                                                                                 
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)