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Pub. No.:    WO/2005/066184    International Application No.:    PCT/IN2004/000430
Publication Date: 21.07.2005 International Filing Date: 30.12.2004
Chapter 2 Demand Filed:    29.07.2005    
C07D 487/04 (2006.01), C07D 513/04 (2006.01)
Applicants: SUVEN LIFE SCIENCES LIMITED [IN/IN]; Serene Chambers, Road No. 7, Banjara Hills, Hyderabad 500 034, Andhra Pradesh (IN) (For All Designated States Except US).
JASTI, Venkateswarlu [US/IN]; (IN) (For US Only).
RAMAKRISHNA, Venkata, Satya, Nirogi [IN/IN]; (IN) (For US Only).
KAMBHAMPATI, Rama, Sastri [IN/IN]; (IN) (For US Only).
SHIRSATH, Vikas, Shreekrishna [IN/IN]; (IN) (For US Only).
VISHWOTTAM, Nagaraj, Kandikere [IN/IN]; (IN) (For US Only)
Inventors: JASTI, Venkateswarlu; (IN).
RAMAKRISHNA, Venkata, Satya, Nirogi; (IN).
KAMBHAMPATI, Rama, Sastri; (IN).
SHIRSATH, Vikas, Shreekrishna; (IN).
VISHWOTTAM, Nagaraj, Kandikere; (IN)
Agent: SUBRAMANIAM, Hariharan; Subramaniam, Nataraj and Associates, E-556 Greater Kailash II, New Delhi 110 048, Maharashtra (IN)
Priority Data:
5/CHE/2004 02.01.2004 IN
Abstract: front page image
(EN)The present invention describes Indeno[2,1a]indene and isoindolo[2,1a]indole derivatives, of the Formula (I), its salts and its stereoisomers, wherein X, R1, R2, R3, R4, R6, R7, R8, R9,R11, R12, R13 and R14 are as described in the specification. The invention also provides a method to prepare compound with formula (I), pharmaceutical composition containing such compounds and method to manufacture a medicament. These compounds are useful in the treatment of various CNS disorders, hematological disorders, eating disorders, diseases associated with pain, respiratory diseases, genito-urological disorders, cardio vascular diseases and cancer.
(FR)L'invention concerne des dérivés d'indéno[2,1a]indène et d'isoindolo[2,1a]indole représentés par la formule (I), ainsi que leurs sels et leurs stéréoisomères. X, R1, R2, R3, R4, R6, R7, R8, R9,R11, R12, R13 et R14 sont conformes à la définition du descriptif. L'invention concerne également un procédé permettant de préparer un composé de formule (I), une composition pharmaceutique contenant de tels composés, et un procédé de préparation d'un médicament. Ces composés peuvent être utilisés pour le traitement de divers troubles du SNC, trouble hématologiques, troubles de l'alimentation, pathologies s'accompagnant de douleurs, pathologies respiratoires, troubles génito-urologiques, pathologies cardio-vasculaires et cancers.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)