WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2005066175) CARBAPENEM INTERMEDIATES AND PROCESSES FOR THEIR PREPARATION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/066175    International Application No.:    PCT/GB2005/000034
Publication Date: 21.07.2005 International Filing Date: 07.01.2005
IPC:
C07D 403/06 (2006.01), C07D 477/14 (2006.01)
Applicants: GLAXO GROUP LIMITED [GB/GB]; Glaxo Wellcome House, Berkeley Avenue, Greenford, Middlesex UB6 0NN (GB) (For All Designated States Except US).
HARRIS, Michael, Anthony [GB/GB]; (GB) (For US Only).
HOWIE, Simon, Lancelot [GB/GB]; (GB) (For US Only)
Inventors: HARRIS, Michael, Anthony; (GB).
HOWIE, Simon, Lancelot; (GB)
Agent: WEST, Vivien; GlaxoSmithKline, Corporate Intellectual Property (CN925.1), 980 Great West Road, Brentford, Middlesex TW8 9GS (GB)
Priority Data:
0400405.7 09.01.2004 GB
Title (EN) CARBAPENEM INTERMEDIATES AND PROCESSES FOR THEIR PREPARATION
(FR) NOUVEAUX PROCEDES
Abstract: front page image
(EN)The cyclization of compounds of formula (II) to carbapenem compounds of formula (III). wherein R1 is an oxygen protecting group, such as a silyl ether e.g. TBS and R is a readily removable carboxy protecting group, may be used in an improved process to prepare antibacterial compounds of formula (I).
(FR)L'invention concerne la cyclisation de composés de formule (II) en composés carbapénèmes de formule (III), formules dans lesquelles R1 désigne un groupe protecteur oxygène, tel qu'un silyl éther, par exemple, TBS, et R désigne un groupe protecteur carboxy, facilement éliminable. La cyclisation précitée peut être utilisée dans un procédé amélioré de préparation de composés antibactériens de formule (I).
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)