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1. (WO2005065018) CRYSTALLINE FORMS OF (6R) -L-ERYTHRO-TETRAHYDROBIOPTERIN DIHYDROCHLORIDE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/065018    International Application No.:    PCT/IB2004/004447
Publication Date: 21.07.2005 International Filing Date: 17.11.2004
IPC:
C07D 475/04 (2006.01)
Applicants: MERCK EPROVA AG [CH/CH]; Im Laternenacker 5, CH-8200 Schaffhausen (CH) (For All Designated States Except US).
MOSER, Rudolf [CH/CH]; (CH) (For US Only).
GROEHN, Viola [CH/CH]; (CH) (For US Only).
EGGER, Thomas [CH/CH]; (CH) (For US Only).
BLATTER, Fritz [CH/CH]; (CH) (For US Only)
Inventors: MOSER, Rudolf; (CH).
GROEHN, Viola; (CH).
EGGER, Thomas; (CH).
BLATTER, Fritz; (CH)
Priority Data:
60/520,377 17.11.2003 US
Title (EN) CRYSTALLINE FORMS OF (6R) -L-ERYTHRO-TETRAHYDROBIOPTERIN DIHYDROCHLORIDE
(FR) FORMES CRISTALLINES DE DIHYDROCHLORURE DE (6R)-L-ERYTHRO-TETRAHYDROBIOPTERINE
Abstract: front page image
(EN)Crystal forms of (6R)-L-erythro-tetrahydrobiopterin dihydrochloride, hydrates and solvates and processes for their preparation are provided. These crystal forms are either intermedi­ates for the preparation of stable polymorphic form B or are suitable for solid formulations.
(FR)L'invention concerne des formes cristallines de dihydrochlorure de (6R)-L-érythro-tétrahydrobioptérine, des hydrates, des solvates et leurs procédés de préparation. Ces formes cristallines sont des produits intermédiaires destinés à la préparation d'une forme B polymorphe stable ou conviennent pour des préparations solides.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)