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1. WO2005063967 - INDUCTION OF MYOCARDIAL CELL WITH THE USE OF MAMMALIAN BONE MARROW CELL OR CORD BLOOD-ORIGIN CELL AND FAT TISSUE

Publication Number WO/2005/063967
Publication Date 14.07.2005
International Application No. PCT/JP2004/019666
International Filing Date 21.12.2004
IPC
A61L 27/38 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27Materials for prostheses or for coating prostheses
36containing ingredients of undetermined constitution or reaction products thereof
38Animal cells
CPC
A61L 27/3826
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27Materials for ; grafts or; prostheses or for coating ; grafts or; prostheses
36containing ingredients of undetermined constitution or reaction products thereof ; , e.g. transplant tissue, natural bone, extracellular matrix
38containing added animal cells
3804characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
3826Muscle cells, e.g. smooth muscle cells
A61L 27/383
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27Materials for ; grafts or; prostheses or for coating ; grafts or; prostheses
36containing ingredients of undetermined constitution or reaction products thereof ; , e.g. transplant tissue, natural bone, extracellular matrix
38containing added animal cells
3804characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
383Nerve cells, e.g. dendritic cells, Schwann cells
A61L 27/3839
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27Materials for ; grafts or; prostheses or for coating ; grafts or; prostheses
36containing ingredients of undetermined constitution or reaction products thereof ; , e.g. transplant tissue, natural bone, extracellular matrix
38containing added animal cells
3839characterised by the site of application in the body
A61L 27/3895
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27Materials for ; grafts or; prostheses or for coating ; grafts or; prostheses
36containing ingredients of undetermined constitution or reaction products thereof ; , e.g. transplant tissue, natural bone, extracellular matrix
38containing added animal cells
3895using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
C12N 2502/1305
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2502Coculture with; Conditioned medium produced by
13connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
1305Adipocytes
C12N 5/0657
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor;
06Animal cells or tissues; Human cells or tissues
0602Vertebrate cells
0652Cells of skeletal and connective tissues; Mesenchyme
0657Cardiomyocytes; Heart cells
Applicants
  • 有限会社金沢大学ティ・エル・オー KANAZAWA UNIVERSITY TECHNOLOGY LICENSING ORGANIZATION LTD. [JP]/[JP] (AllExceptUS)
  • 独立行政法人科学技術振興機構 JAPAN SCIENCE AND TECHNOLOGY AGENCY [JP]/[JP] (AllExceptUS)
  • 高倉 伸幸 TAKAKURA, Nobuyuki [JP]/[JP] (UsOnly)
  • YAMADA, Yoshihiro [JP]/[JP] (UsOnly)
Inventors
  • 高倉 伸幸 TAKAKURA, Nobuyuki
  • YAMADA, Yoshihiro
Agents
  • 平木 祐輔 HIRAKI, Yusuke
Priority Data
2003-42908825.12.2003JP
Publication Language Japanese (JA)
Filing Language Japanese (JA)
Designated States
Title
(EN) INDUCTION OF MYOCARDIAL CELL WITH THE USE OF MAMMALIAN BONE MARROW CELL OR CORD BLOOD-ORIGIN CELL AND FAT TISSUE
(FR) TECHNIQUE POUR INDUIRE LA DIFFERENCIATION DE CELLULES DE MOELLE OSSEUSE DE MAMMIFERES OU DE CELLULES DE SANG DE CORDON OMBILICAL EN CELLULES MYOCARDIQUES AU MOYEN DE TISSU ADIPEUX
(JA) 哺乳動物の骨髄細胞または臍帯血由来細胞と脂肪組織を利用した心筋細胞の誘導
Abstract
(EN)
It is intended to provide a technique of inducing the differentiation of mammalian bone marrow cells or cord blood-origin cells into myocardial cell precursors and/or myocardial cells by culturing the mammalian bone marrow cells or cord blood-origin cells together with cells isolated from a mammalian fat tissue or a culture supernatant thereof.
(FR)
L'invention concerne une technique pour induire la différenciation de cellules de moelle osseuse de mammifères ou de cellules provenant de sang de cordon ombilical en précurseurs de cellules myocardiques et/ou en cellules myocardiques, par mise en culture des cellules de moelle osseuse de mammifères ou des cellules provenant de sang de cordon ombilical avec des cellules isolées dans un tissu adipeux mammalien ou un surnageant de culture.
(JA)
本発明は、哺乳動物の骨髄細胞または臍帯血由来細胞を、哺乳動物の脂肪組織から単離された細胞またはその培養上清とともに培養することにより、該骨髄細胞または臍帯血由来細胞を心筋前駆細胞および/または心筋細胞に分化誘導する技術を提供する。
Also published as
EP2009003644
US2007212676
Latest bibliographic data on file with the International Bureau