WO2005063757 NOVEL CRYSTALLINE FORMS OF TEMOZOLOMIDE

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Publication Number WO/2005/063757

Publication Date 14.07.2005

International Application No. PCT/IL2004/001189

International Filing Date 30.12.2004

IPC

CPC

Applicants

CHEMAGIS LTD. [IL]/[IL] (AllExceptUS)
ADIN, Itai [IL]/[IL] (UsOnly)
IUSTAIN, Carmen [IL]/[IL] (UsOnly)

Inventors

ADIN, Itai
IUSTAIN, Carmen

Agents

G.E. EHRLICH (1995) LTD.

Priority Data

60/532,944

30.12.2003

Publication Language English (en)

Filing Language English (EN)

Designated States

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Title

(EN) NOVEL CRYSTALLINE FORMS OF TEMOZOLOMIDE

(FR) NOUVELLES FORMES CRISTALLINES DE TEMOZOLOMIDE

Abstract

(EN) Disclosed are novel crystalline forms of Temozolomide, methods of preparation thereof, medicaments including the novel crystalline forms of Temozolomide, and uses thereof in the treatment of medical conditions.

(FR) Cette invention concerne des nouvelles formes cristallines de Temozolomide, leurs méthodes de fabrication, des médicaments renfermant lesdites formes cristallines et leurs utilisations au plan médical.

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
33	Heterocyclic compounds
395	having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41	having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
4164	1,3-Diazoles
4188	condensed with heterocyclic ring systems, e.g. biotin, sorbinil

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
D	HETEROCYCLIC COMPOUNDS
487	Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/-C07D477/183
02	in which the condensed system contains two hetero rings
04	Ortho-condensed systems

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
33	Heterocyclic compounds
395	having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41	having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
4164	1,3-Diazoles
4188	condensed with heterocyclic ring systems, e.g. biotin, sorbinil

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
D	HETEROCYCLIC COMPOUNDS
487	Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/-C07D477/183
02	in which the condensed system contains two hetero rings
04	Ortho-condensed systems

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
P	SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35	Antineoplastic agents

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1. WO2005063757 - NOVEL CRYSTALLINE FORMS OF TEMOZOLOMIDE