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1. (WO2005063746) PYRROLO[2,3-b]PYRIDINE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/063746    International Application No.:    PCT/EP2004/014674
Publication Date: 14.07.2005 International Filing Date: 23.12.2004
IPC:
C07D 471/04 (2006.01)
Applicants: PFIZER ITALIA S.R.L. [IT/IT]; Via SS 156 Km. 50, I-04100 Latina (IT) (For All Designated States Except US).
SALOM, Barbara [IT/IT]; (IT) (For US Only).
D'ANELLO, Matteo [IT/IT]; (IT) (For US Only).
BRASCA, Maria, Gabriella [IT/IT]; (IT) (For US Only).
GIORDANO, Patrizia [IT/IT]; (IT) (For US Only).
MARTINA, Katia [IT/IT]; (IT) (For US Only).
ANGELUCCI, Francesco [IT/IT]; (IT) (For US Only).
BROOKFIELD, Frederick, Arthur [GB/GB]; (GB) (For US Only).
TRIGG, William, John [GB/GB]; (GB) (For US Only).
BOYD, Edward, Andrew [GB/GB]; (GB) (For US Only).
LARARD, Jonathan, Anthony [GB/GB]; (GB) (For US Only)
Inventors: SALOM, Barbara; (IT).
D'ANELLO, Matteo; (IT).
BRASCA, Maria, Gabriella; (IT).
GIORDANO, Patrizia; (IT).
MARTINA, Katia; (IT).
ANGELUCCI, Francesco; (IT).
BROOKFIELD, Frederick, Arthur; (GB).
TRIGG, William, John; (GB).
BOYD, Edward, Andrew; (GB).
LARARD, Jonathan, Anthony; (GB)
Agent: MODIANO, Micaela, Nadia; Modiano Josif Pisanty & Staub, Baaderstrasse 3, 80469 Munich (DE)
Priority Data:
0330043.3 24.12.2003 GB
Title (EN) PYRROLO[2,3-b]PYRIDINE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM
(FR) DERIVES PYRROLO[2,3-B]PYRIDINE AGISSANT COMME INHIBITEURS DES KINASES, PROCEDE POUR LEUR ELABORATION, ET COMPOSITIONS PHARMACEUTIQUES LES COMPRENANT
Abstract: front page image
(EN)Compounds which are pyrrolo[2,3-b]pyridine derivatives or pharmaceutically acceptable salts thereof, their preparation process and pharmaceutical compositions comprising them are disclosed; these compounds are useful in the treatment of diseases caused by and/or associated with an altered protein kinase activity such as cancer, cell proliferative disorders, Alzheimer's disease, viral infections, auto-immune diseases and neurodegenerative disorders; also disclosed is a process under SPS conditions for preparing the compounds of the invention and chemical libraries comprising a plurality of them.
(FR)La présente invention concerne des composés à base de dérivés de pyrrolo[2,3-b]pyridine ou de certains de leurs sels pharmaceutiquement admis, des procédés d'élaboration correspondants, et des compositions pharmaceutiques à base de ces composés. Ces composés conviennent au traitement d'affections causées par et/ou associées à une activité altérée des protéine kinases, et notamment le cancer, les troubles à prolifération cellulaire, la maladie d'Alzheimer, des infections virales, des affections auto-immunes, et des troubles neurodégénératifs. L'invention concerne également un processus sous SPS permettant l'élaboration des composés de l'invention, et des échantillothèques comprenant une pluralité de ces composés.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)