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Machine translation
1. (WO2005063248) MODAFINIL COMBINATION THERAPY FOR IMPROVING SLEEP QUALITY
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/063248    International Application No.:    PCT/US2004/042938
Publication Date: 14.07.2005 International Filing Date: 21.12.2004
IPC:
A61K 31/495 (2006.01), A61K 45/06 (2006.01)
Applicants: SEPRACOR INC. [US/US]; 84 Waterford Drive, Marlborough, MA 01752-7010 (US) (For All Designated States Except US).
LALJI, Karim [--/US]; (US) (For US Only).
BARBERICH, Timothy, J. [US/US]; (US) (For US Only)
Inventors: LALJI, Karim; (US).
BARBERICH, Timothy, J.; (US)
Agent: GORDON, Dana, M.; Foley Hoag LLP, Patent Group, 155 Seaport Boulevard, Boston, MA 02210-2698 (US)
Priority Data:
60/531,822 22.12.2003 US
60/541,684 04.02.2004 US
Title (EN) MODAFINIL COMBINATION THERAPY FOR IMPROVING SLEEP QUALITY
(FR) THERAPIE COMBINATOIRE AVEC LA MODAFINILE POUR AMELIORER LA QUALITE DU SOMMEIL
Abstract: front page image
(EN)One aspect of the present invention relates to pharmaceutical compositions comprising a compound that modulates the orexin system and a sedative agent. In a preferred embodiment, the compound that modulates the orexin system is modafinil and the sedative agent is (S)-zopiclone. The pharmaceutical compositions of the invention are useful in the treatment of various sleep disorders. In addition, the present invention relates to a method of treating a patient suffering from a sleep abnormality or insomnia comprising administering a therapeutically effective amount of a pharmaceutical composition of the invention.
(FR)L'invention concerne des compositions pharmaceutiques comprenant un composé qui module le système des orexines et un agent sédatif. Dans un mode de réalisation préféré, le composé qui module le système des orexines est la modafinile et l'agent sédatif est (S)-zopiclone. Les compositions pharmaceutiques de l'invention sont utiles dans le traitement de divers troubles du sommeil. La présente invention porte également sur une méthode pour traiter un patient souffrant de troubles du sommeil ou d'insomnie, cette méthode consistant à administrer une dose thérapeutiquement efficace d'une composition pharmaceutique de l'invention.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)