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Pub. No.:    WO/2005/061457    International Application No.:    PCT/EP2004/052389
Publication Date: 07.07.2005 International Filing Date: 30.09.2004
A61K 31/395 (2006.01), C07D 211/42 (2006.01), C07D 401/12 (2006.01), C07D 413/12 (2006.01)
Applicants: SPEEDEL EXPERIMENTA AG [CH/CH]; Gewerbestrasse 14, CH-4123 Allschwil (CH) (For All Designated States Except US).
HEROLD, Peter [CH/CH]; (CH) (For US Only).
MAH, Robert [CA/CH]; (CH) (For US Only).
STUTZ, Stefan [CH/CH]; (CH) (For US Only).
STOJANOVIC, Aleksandar [CH/CH]; (CH) (For US Only).
TSCHINKE, Vincenzo [IT/CH]; (CH) (For US Only).
JOTTERAND, Nathalie [CH/CH]; (CH) (For US Only)
Inventors: HEROLD, Peter; (CH).
MAH, Robert; (CH).
STUTZ, Stefan; (CH).
STOJANOVIC, Aleksandar; (CH).
TSCHINKE, Vincenzo; (CH).
JOTTERAND, Nathalie; (CH)
Agent: MAUÉ, Paul Georg; Solvias AG, Patents, WKL-402.3.04, Klybeckstrasse 191, CH-4002 Basel (CH)
Priority Data:
1669/03 01.10.2003 CH
0343/04 27.02.2004 CH
Abstract: front page image
(EN)Novel substituted piperidines of the general formulae (I) and (II) with the substituent definitions as explained in detail in the description are described. The compounds are suitable in particular as renin inhibitors and are highly potent.
(FR)La présente invention a trait à de nouveaux pipéridines substitués de formules générales (I) et (II), les substituants étant tels que définis dans le détail dans la description. Les composés sont appropriés notamment en tant qu'inhibiteurs de la rénine et sont extrêmement efficaces.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)