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1. (WO2005060956) IMMUNOMODULATORY COMPOUNDS THAT TARGET AND INHIBIT THE pY+3 BINDING SITE OF TYROSENE KINASE p56 LCK SH2 DOMAIN
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/060956    International Application No.:    PCT/US2003/039501
Publication Date: 07.07.2005 International Filing Date: 12.12.2003
IPC:
A61K 31/33 (2006.01)
Applicants: UNIVERSITY OF MARYLAND, BALTIMORE [US/US]; 520 West Lombard Street, Baltimore, MD 21201 (US) (For All Designated States Except US).
MACKERELL, Alexander, D., Jr. [US/US]; (US) (For US Only).
HAYASHI, Jun [US/US]; (US) (For US Only).
NAGARSEKAR, Ashish [IN/US]; (US) (For US Only).
HUANG, Niu [CN/US]; (US) (For US Only).
MACIAS, Alba [US/US]; (US) (For US Only)
Inventors: MACKERELL, Alexander, D., Jr.; (US).
HAYASHI, Jun; (US).
NAGARSEKAR, Ashish; (US).
HUANG, Niu; (US).
MACIAS, Alba; (US)
Agent: SOPP, John, A.; Millen, White, Zelano & branigan, P.C., Arlington Courthouse Plaza 1, 2200 Clarendon Boulevard, Suite 1400, Arlington, VA 22201 (US)
Priority Data:
Title (EN) IMMUNOMODULATORY COMPOUNDS THAT TARGET AND INHIBIT THE pY+3 BINDING SITE OF TYROSENE KINASE p56 LCK SH2 DOMAIN
(FR) COMPOSES IMMUNOMODULATEURS DE CIBLAGE ET D'INHIBITION DU SITE DE LIAISON PY+3 DU DOMAINE SH2 DE LA PROTEINE P56 TYROSINE KINASE
Abstract: front page image
(EN)Small molecular-weight non-peptidic compounds block Lck SH2 domain-dependent interactions. The inhibitors omit phosphotyrosine (pY) or related moieties.
(FR)La présente invention a trait à des composés non peptidiques de faible poids moléculaire de blocage des interactions dépendant du domaine Lck SH2. Les inhibiteurs éliminent la phosphotyrosine (pY) ou des groupes fonctionnels associés.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)