WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2005060479) PURIFIED AND ISOLATED PLATELET CALCIUM CHANNEL NUCLEIC ACIDS AND POLYPEPTIDES AND THERAPEUTIC AND SCREENING METHODS USING SAME
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/060479    International Application No.:    PCT/US2004/038442
Publication Date: 07.07.2005 International Filing Date: 16.11.2004
IPC:
G01N 33/53 (2006.01), G01N 33/567 (2006.01), C07K 14/435 (2006.01), C07H 21/04 (2006.01), C12P 21/02 (2006.01), C12N 5/06 (2006.01)
Applicants: UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL [US/US]; 308 Bynum Hall, Campus Box 4105, Chapel Hill, NC 27599-4105 (US) (For All Designated States Except US).
NICHOLS, Timothy, C. [US/US]; (US) (For US Only).
MALOUF, Nadia [US/US]; (US) (For US Only).
MERRICKS, Elizabeth [US/US]; (US) (For US Only)
Inventors: NICHOLS, Timothy, C.; (US).
MALOUF, Nadia; (US).
MERRICKS, Elizabeth; (US)
Agent: TAYLOR, Arles, A., Jr.; Jenkins, Wilson & Taylor, P.A., Suite 1400, University Tower, 3100 Tower Boulevard, Durham, NC 27707 (US)
Priority Data:
10/726,216 02.12.2003 US
Title (EN) PURIFIED AND ISOLATED PLATELET CALCIUM CHANNEL NUCLEIC ACIDS AND POLYPEPTIDES AND THERAPEUTIC AND SCREENING METHODS USING SAME
(FR) ACIDES NUCLEIQUES ET POLYPEPTIDES DES CANAUX CALCIQUES PLAQUETTAIRES PURIFIES ET ISOLES ET METHODES DE TRAITEMENT ET DE CRIBLAGE FAISANT APPEL A CEUX-CI
Abstract: front page image
(EN)Isolated and purified platelet voltage dependent calcium channel (VDCC) &agr;1 subunit polypeptides, and nucleic acid molecules encoding the same. Recombinant host cells, recombinant nucleic acids, and recombinant proteins are also disclosed, along with methods of producing each. Isolated and purified antibodies to platelet VDCC &agr;1 subunit polypeptides, and methods of producing the same, are also disclosed. Platelet VDCC &agr;1 subunit polypeptides have biological activity in calcium transport. Thus, therapeutic and diagnostic methods involving this activity are also disclosed.
(FR)L'invention concerne des polypeptides à sous-unités $g(a)1 des canaux calciques voltage-dépendants (VDCC) plaquettaires isolés et purifiés, ainsi que des molécules d'acides nucléiques codant pour ceux-ci. L'invention concerne également des cellules hôtes, des acides nucléiques recombinés et des protéines recombinées, ainsi que leurs procédés de production. Elle se rapporte en outre à des anticorps isolés et purifiés dirigés contre les polypeptides à sous-unités $g(a)1 VDCC plaquettaires, ainsi qu'à leurs procédés de production. Les polypeptides à sous-unités $g(a)1 VDCC plaquettaires exercent une activité biologique dans le transport du calcium. Par conséquent, l'invention porte sur des méthodes thérapeutiques et diagnostiques faisant appel à cette activité.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)