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1. (WO2005054441) DEVICE FOR IMMOBILIZING CHEMICAL AND BIOMEDICAL SPECIES AND METHODS OF USING SAME
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2005/054441 International Application No.: PCT/US2004/040147
Publication Date: 16.06.2005 International Filing Date: 01.12.2004
IPC:
C12Q 1/68 (2006.01) ,F16K 7/04 (2006.01) ,F16K 31/145 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
F MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
16
ENGINEERING ELEMENTS OR UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
K
VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
7
Diaphragm cut-off apparatus, e.g. with a member deformed, but not moved bodily, to close the passage
02
with tubular diaphragm
04
constrictable by external radial force
F MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
16
ENGINEERING ELEMENTS OR UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
K
VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
31
Operating means; Releasing devices
12
actuated by fluid
14
for mounting on, or in combination with, hand-actuated valves
145
the fluid acting on a diaphragm
Applicants:
CALIFORNIA INSTITUTE OF TECHNOLOGY [US/US]; 1200 East California Boulevard Pasadena, CA 91125, US (AllExceptUS)
QUAKE, Stephen, R. [US/US]; US (UsOnly)
KARTALOV, Emil [US/US]; US (UsOnly)
Inventors:
QUAKE, Stephen, R.; US
KARTALOV, Emil; US
Agent:
HAILE, Lisa, A.; Gray Cary Ware & Freidenrich LLP Suite 1100 4365 Executive Drive San Diego, CA 92121-2133, US
Priority Data:
60/526,16201.12.2003US
Title (EN) DEVICE FOR IMMOBILIZING CHEMICAL AND BIOMEDICAL SPECIES AND METHODS OF USING SAME
(FR) DISPOSITIF PERMETTANT D'IMMOBILISER DES ESPECES CHIMIQUES ET BIOCHIMIQUES ET PROCEDES D'UTILISATION CORRESPONDANTS
Abstract:
(EN) A substrate is provided that facilitates immobilization of nucleic acid molecules, including DNA molecules and RNA molecules. Also provided is a device that includes the substrate, which, for example, can be a chip. In addition, methods of using the substrate are provided, including, for example, methods of sequencing a DNA molecule anchored to the substrate, and methods for conducting the process of sequencing using such devices.
(FR) Selon cette invention, on utilise un substrat qui facilite l'immobilisation de molécules d'acide nucléique, y compris de molécules d'ADN et de molécules d'ARN. Cette invention concerne un dispositif qui comprend ce substrat qui peut, par exemple, être une puce. Cette invention concerne en outre des procédés d'utilisation de ce substrat, y compris, par exemple, des procédés de séquençage d'une molécule d'ADN ancrée dans le substrat ainsi que des procédés de mise en oeuvre de ce procédé de séquençage utilisant ces dispositifs.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)