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1. (WO2005054238) 1H-IMIDAZO[4,5-C]QUINOLINE DERIVATIVES IN THE TREATMENT OF PROTEIN KINASE DEPENDENT DISEASES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2005/054238 International Application No.: PCT/EP2004/013179
Publication Date: 16.06.2005 International Filing Date: 19.11.2004
IPC:
A61K 31/41 (2006.01) ,C07D 471/04 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
41
having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
471
Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/-C07D463/251
02
in which the condensed system contains two hetero rings
04
Ortho-condensed systems
Applicants:
NOVARTIS AG [CH/CH]; Lichtstrasse 35 CH-4056 Basel, CH (AE, AG, AL, AM, AU, AZ, BA, BB, BE, BF, BG, BJ, BR, BW, BY, BZ, CA, CF, CG, CH, CI, CM, CN, CO, CR, CU, CY, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GW, HR, HU, ID, IE, IL, IN, IS, IT, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MC, MD, MG, MK, ML, MN, MR, MW, MX, MZ, NA, NE, NI, NL, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SI, SK, SL, SN, SY, SZ, TD, TG, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, YU, ZA, ZM, ZW)
NOVARTIS PHARMA GMBH [AT/AT]; Brunner Strasse 59 A-1230 Vienna, AT (AT)
CAPRARO, Hans-Georg [CH/CH]; CH (UsOnly)
FURET, Pascal [FR/FR]; FR (UsOnly)
GARCIA-ECHEVERRIA, Carlos [ES/CH]; CH (UsOnly)
STAUFFER, Frédéric [CH/CH]; CH (UsOnly)
Inventors:
CAPRARO, Hans-Georg; CH
FURET, Pascal; FR
GARCIA-ECHEVERRIA, Carlos; CH
STAUFFER, Frédéric; CH
Agent:
GRUBB, Philip; Novartis AG Corporate Intellectual Property CH-4002 Basel, CH
Priority Data:
60/524,21421.11.2003US
Title (EN) 1H-IMIDAZO[4,5-C]QUINOLINE DERIVATIVES IN THE TREATMENT OF PROTEIN KINASE DEPENDENT DISEASES
(FR) DERIVES D'1H-IMIDAZO[4,5-C]QUINOLINE DANS LE TRAITEMENT DE MALADIES DEPENDANT DE LA PROTEINE KINASE
Abstract:
(EN) The invention relates to the use of imidazoquinolines and salts thereof in the treatment of protein kinase diseases and for the manufacture of pharmaceutical preparations for the treatment of said diseases, imidazoquinolines for use in the treatment of protein kinase dependent diseases, a method of treatment against said diseases, comprising administering the imidazoquinolines to a warm-blooded animal, especially a human, pharmaceutical preparations comprising an imidazoquinoline, especially for the treatment of a protein kinase dependent disease, novel imidazoquinolines, and a process for the preparation of the novel imidazoquinolines.
(FR) L'invention concerne l'utilisation d'imidazoquinolines et de leurs sels dans le traitement de maladies dépendant de la protéine kinase et dans la fabrication de préparations pharmaceutiques destinées au traitement desdites maladies. Cette invention a aussi pour objet des imidazoquinolines utilisées dans le traitement de maladies dépendant de la protéine kinase et une méthode de traitement desdites maladies qui consiste à administrer les imidazoquinolines à un animal à sang chaud, notamment, un être humain. Ladite invention concerne également des préparations pharmaceutiques contenant une imidazoquinoline, plus spécifiquement, dans le traitement d'une maladie dépendant de la protéine kinase, des nouvelles imidazoquinolines, et un processus de préparation des nouvelles imidazoquinolines.
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Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
MXPA/a/2006/005701BRPI0416796EP1689747JP2007511576US20070213355CN1882586
CA2541691AU2004295062TH73461IN1780/CHENP/2006