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1. (WO2005040167) NOVEL DIAZASPIROALKANES AND THEIR USE FOR TREATMENT OF CCR8 MEDIATED DISEASES
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2005/040167 International Application No.: PCT/SE2004/001522
Publication Date: 06.05.2005 International Filing Date: 21.10.2004
IPC:
C07D 471/10 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
471
Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/-C07D463/251
02
in which the condensed system contains two hetero rings
10
Spiro-condensed systems
Applicants:
BLADH, Håkan [SE/SE]; SE (UsOnly)
CONNOLLY, Stephen [GB/GB]; GB (UsOnly)
DYKE, Hazel Joan [GB/GB]; GB (UsOnly)
LISIUS, Annea [SE/SE]; SE (UsOnly)
PRICE, Stephen [GB/GB]; GB (UsOnly)
SHAMOVSKY, Igor [CA/SE]; SE (UsOnly)
VAN DEN HEUVEL, Marco [NL/GB]; GB (UsOnly)
ASTRAZENECA AB [SE/SE]; S-151 85 Södertälje, SE (AllExceptUS)
Inventors:
BLADH, Håkan; SE
CONNOLLY, Stephen; GB
DYKE, Hazel Joan; GB
LISIUS, Annea; SE
PRICE, Stephen; GB
SHAMOVSKY, Igor; SE
VAN DEN HEUVEL, Marco; GB
Agent:
ASTRAZENECA; Global Intellectual Property S-151 85 Södertälje, SE
Priority Data:
0302811-523.10.2003SE
Title (EN) NOVEL DIAZASPIROALKANES AND THEIR USE FOR TREATMENT OF CCR8 MEDIATED DISEASES
(FR) NOUVEAUX DIAZASPIROALCANES ET LEUR UTILISATION DANS LE TRAITEMENT DE MALADIES INDUITES PAR CCR8
Abstract:
(EN) The invention provides compounds of general formula. wherein A, B, W, X, Y, Z, D, E, R1 and n are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
(FR) L'invention concerne des composés représentés par la formule générale (I). Dans cette formule A, B, W, X, Y, Z, D, E, R1 et n sont définis comme dans la description. L'invention concerne également des procédés de préparation de ces composés, des compositions pharmaceutiques les contenant et leur utilisation thérapeutique.
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Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)