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1. WO2005040167 - NOVEL DIAZASPIROALKANES AND THEIR USE FOR TREATMENT OF CCR8 MEDIATED DISEASES

Publication Number WO/2005/040167
Publication Date 06.05.2005
International Application No. PCT/SE2004/001522
International Filing Date 21.10.2004
IPC
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
471
Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/-C07D463/251
02
in which the condensed system contains two hetero rings
10
Spiro-condensed systems
C07D 471/10 (2006.01)
CPC
C07D 471/10
Applicants
  • ASTRAZENECA AB [SE/SE]; S-151 85 Södertälje, SE (AllExceptUS)
  • BLADH, Håkan [SE/SE]; SE (UsOnly)
  • CONNOLLY, Stephen [GB/GB]; GB (UsOnly)
  • DYKE, Hazel Joan [GB/GB]; GB (UsOnly)
  • LISIUS, Annea [SE/SE]; SE (UsOnly)
  • PRICE, Stephen [GB/GB]; GB (UsOnly)
  • SHAMOVSKY, Igor [CA/SE]; SE (UsOnly)
  • VAN DEN HEUVEL, Marco [NL/GB]; GB (UsOnly)
Inventors
  • BLADH, Håkan; SE
  • CONNOLLY, Stephen; GB
  • DYKE, Hazel Joan; GB
  • LISIUS, Annea; SE
  • PRICE, Stephen; GB
  • SHAMOVSKY, Igor; SE
  • VAN DEN HEUVEL, Marco; GB
Agents
  • ASTRAZENECA; Global Intellectual Property S-151 85 Södertälje, SE
Priority Data
0302811-523.10.2003SE
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) NOVEL DIAZASPIROALKANES AND THEIR USE FOR TREATMENT OF CCR8 MEDIATED DISEASES
(FR) NOUVEAUX DIAZASPIROALCANES ET LEUR UTILISATION DANS LE TRAITEMENT DE MALADIES INDUITES PAR CCR8
Abstract
(EN)
The invention provides compounds of general formula. wherein A, B, W, X, Y, Z, D, E, R1 and n are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
(FR)
L'invention concerne des composés représentés par la formule générale (I). Dans cette formule A, B, W, X, Y, Z, D, E, R1 et n sont définis comme dans la description. L'invention concerne également des procédés de préparation de ces composés, des compositions pharmaceutiques les contenant et leur utilisation thérapeutique.
Latest bibliographic data on file with the International Bureau