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1. (WO2005038041) DIRECT NUCLEIC ACID DETECTION IN BODILY FLUIDS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/038041    International Application No.:    PCT/US2004/034279
Publication Date: 28.04.2005 International Filing Date: 18.10.2004
IPC:
C12Q 1/68 (2006.01), C12P 19/34 (2006.01), C07H 21/02 (2006.01)
Applicants: THIRD WAVE TECHNOLOGIES, INC. [US/US]; 502 South Rosa Road, Madison, WI 53719-1256 (US) (For All Designated States Except US).
LYAMICHEV, Victor [RU/US]; (US) (For US Only).
LUKOWIAK, Andrew, A. [US/US]; (US) (For US Only).
JARVIS, Nancy [CN/US]; (US) (For US Only).
ROEVEN, Robert [NL/US]; (US) (For US Only).
HALL, Jeff, G. [US/US]; (US) (For US Only).
ALLAWI, Hatim, T. [JO/US]; (US) (For US Only)
Inventors: LYAMICHEV, Victor; (US).
LUKOWIAK, Andrew, A.; (US).
JARVIS, Nancy; (US).
ROEVEN, Robert; (US).
HALL, Jeff, G.; (US).
ALLAWI, Hatim, T.; (US)
Agent: CASIMIR, David, A.; Medlen & Carroll, LLP, 101 Howard Street, Suite 350, San Francisco, CA 94105 (US)
Priority Data:
60/511,955 16.10.2003 US
60/549,527 02.03.2004 US
60/551,669 09.03.2004 US
  18.10.2004 US
Title (EN) DIRECT NUCLEIC ACID DETECTION IN BODILY FLUIDS
(FR) DETECTION DIRECTE D'ACIDES NUCLEIQUES DANS DES LIQUIDES ORGANIQUES
Abstract: front page image
(EN)The present invention provides methods and routines for developing and optimizing nucleic acid detection assays for use in basic research, clinical research, and for the development of clinical detection assays. In particular, the present invention provides methods for designing oligonucleotide primers to be used in multiplex amplification reactions. The present invention also provides methods to optimize multiplex amplification reactions. The present invention also provides methods for combined target and signal generation assays.
(FR)L'invention concerne des méthodes et des routines médicales permettant de développer et d'optimiser des essais de détection d'acide nucléique destinés à être utilisés dans la recherche fondamentale, la recherche clinique, et pour le développement d'essais de détection clinique. L'invention porte notamment sur des méthodes de conception d'amorces oligonucléotidiques destinées être utilisées dans des réactions d'amplification multiplex. L'invention se rapporte aussi à des méthodes d'optimisation de réactions d'amplification multiplex, ainsi qu'à des méthodes d'essais de génération de signaux et de cibles combinés.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)