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1. (WO2005037798) AMIDE OR THIOMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF PAIN
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2005/037798 International Application No.: PCT/US2004/033698
Publication Date: 28.04.2005 International Filing Date: 14.10.2004
Chapter 2 Demand Filed: 17.05.2005
IPC:
C07C 237/22 (2006.01) ,C07C 279/28 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
237
Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
02
having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
22
having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
279
Derivatives of guanidine, i.e. compounds containing the group the singly-bound nitrogen atoms not being part of nitro or nitroso groups
28
having nitrogen atoms of guanidine groups bound to cyano groups, e.g. cyanoguanidines, dicyandiamides
Applicants: CHANG, Chia-Ping[US/US]; US (UsOnly)
STALEWSKI, Jacek[PL/US]; US (UsOnly)
RIVIERE , Pierre, J-M.[FR/US]; US (UsOnly)
WISNIEWSKI , Kazimierz, A.[PL/US]; US (UsOnly)
SCHTEINGART , Claudio, D.[US/US]; US (UsOnly)
CARA THERAPEUTICS, INC[US/US]; 765 Old Saw Mill River Road Tarrytown NY 10591, US (AllExceptUS)
Inventors: CHANG, Chia-Ping; US
STALEWSKI, Jacek; US
RIVIERE , Pierre, J-M.; US
WISNIEWSKI , Kazimierz, A.; US
SCHTEINGART , Claudio, D.; US
Agent: SIMPSON Suzanne L.; PILLSBURY WINTHROP LLP 11682 El Camino Real, Suite 200 San Diego, California 92130, US
Vossius & Partner; Siebertstrasse 4 81675 Munchen, DE
Priority Data:
60/511,57716.10.2003US
Title (EN) AMIDE OR THIOMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF PAIN
(FR) NOUVEAUX COMPOSÉS
Abstract:
(EN) The present invention relates to novel compounds, pharmaceutical compositions comprising the same, use of said compounds for the manufacture of a medicament for treatment of pain and disorders related thereto as well as a method for treatment of pain and disorders related thereto, wherein said compounds are administered. The compounds are represented by the general formula (I), as further defined in the specification.
(FR) L'invention concerne de nouveaux composés, des compositions pharmaceutiques contenant ces composés, l'utilisation de ces composés dans la fabrication d'un médicament utilisé pour traiter la douleur et les troubles afférents ainsi qu'une méthode de traitement de la douleur et des troubles afférents qui repose sur l'administration de ces composés. Ces composés sont représentés par la formule générale (I), tels que définis dans le descriptif.
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Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)