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Machine translation
1. (WO2005037289) ANALGESIA METHOD
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/037289    International Application No.:    PCT/GB2004/004389
Publication Date: 28.04.2005 International Filing Date: 15.10.2004
IPC:
A61K 31/485 (2006.01), A61K 31/57 (2006.01), A61K 31/573 (2006.01)
Applicants: VERNALIS (CAMBRIDGE) LIMITED [GB/GB]; Granta Park, Abington, Cambridge CB1 6GB (GB) (For All Designated States Except US).
GOODCHILD, Colin, Stanley [AU/AU]; (AU) (For US Only).
NADESON, Raymond [AU/AU]; (AU) (For US Only)
Inventors: GOODCHILD, Colin, Stanley; (AU).
NADESON, Raymond; (AU)
Agent: WALLS, Alan, James; Vernalis (Cambridge) Limited, Granta Park, Abington, Cambridge CB1 6GB (GB)
Priority Data:
0324423.3 18.10.2003 GB
Title (EN) ANALGESIA METHOD
(FR) METHODE D'ANALGESIE
Abstract: front page image
(EN)Opioid tolerance is reduced by treating the patient with a neurosteroid of formula (I) wherein R1 is H or methyl; R2 is OH and R3 is H, or R2 and R3 taken together are O; R4 is H or methyl; R5 and R6 are each H, or R5 and R5 taken together are O; R7 is H or methyl; and R8 is H, OH, -OC(=O)CH3, SH, -SC(=O)CH3, Cl, Br or F.
(FR)La tolérance aux opiacés peut être réduite par traitement du patient au moyen d'un neurostéroïde représenté par la formule (I) dans cette formule, R1 est H ou méthyle; R2 est OH et R3 est H, ou R2 et R3 pris ensemble sont O; R4 est H ou méthyle; R5 et R6 sont chacun H, ou R5 et R5 pris ensemble sont O; R7 est H ou méthyle; et R8 est H, OH, -OC(=O)CH3, SH, -SC(=O)CH3, Cl, Br ou F.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)