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1. (WO2005035556) SARS-CORONAVIRUS VIRUS-LIKE PARTICLES AND METHODS OF USE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/035556    International Application No.:    PCT/US2004/013966
Publication Date: 21.04.2005 International Filing Date: 04.05.2004
IPC:
A61K 39/215 (2006.01), C07K 14/165 (2006.01), C12N 7/00 (2006.01), C12N 7/04 (2006.01), C12Q 1/70 (2006.01)
Applicants: IGUAZU BIOSCIENCES CORP. [US/US]; 1401 Camino del Mar, Suite 202, Del Mar, California 92104 (US) (For All Designated States Except US).
TECHOLDING S.A. [LU/LU]; 5, boulevard de la Foire, L-2013 Luxembourg (LU) (For All Designated States Except US).
HEROLD, Jens [DE/DE]; (DE) (For US Only)
Inventors: HEROLD, Jens; (DE)
Agent: HART, Daniel; KNOBBE, MARTENS, OLSON & BEAR, LLP, 2040 Main Street, 14th Floor, Irvine, California 92614 (US)
Priority Data:
60/468,703 06.05.2003 US
Title (EN) SARS-CORONAVIRUS VIRUS-LIKE PARTICLES AND METHODS OF USE
(FR) PARTICULES PSEUDO-VIRALES DU CORONAVIRUS DU SRAS ET METHODES D'UTILISATION
Abstract: front page image
(EN)The present disclosure describes a system for making SARS-CoV-virus-like particles (SARS-CoV-VLPs) comprising one or more recombinant vectors which express the SARS-CoV E-protein, the SARS-CoV M-protein, and the SARS-CoV S-protein. Additionally, the present disclosure describes methods of inducing an immune response in a subject comprising administering to the subject a nucleic acid encoding the SARS-CoV E-protein, the SARS-CoV M-protein, and the SARS-CoV S-protein. Methods of inducing an immune response in a subject comprising administering to the subject SARS-CoV-VLPs are also disclosed.
(FR)L'invention concerne un système de fabrication de particules pseudo-virales du coronavirus du SRAS (CoV-SRAS VLP) contenant au moins un vecteur recombiné exprimant la protéine CoV-SRAS E, la protéine CoV-SRAS M et la protéine CoV-SRAS S. L'invention concerne également des méthodes destinées à induire une réponse immunitaire chez un sujet, ces méthodes consistant à administrer au sujet un acide nucléique codant la protéine CoV-SRAS E, la protéine CoV-SRAS M et la protéine CoV-SRAS S. L'invention concerne encore des méthodes destinées à induire une réponse immunitaire chez un sujet, ces méthodes consistant à administrer au sujet des particules pseudo-virales du CoV-SRAS.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)