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1. (WO2005035533) MODULATORS OF SEROTONIN RECEPTORS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2005/035533 International Application No.: PCT/US2004/032849
Publication Date: 21.04.2005 International Filing Date: 06.10.2004
IPC:
C07D 471/04 (2006.01) ,C07D 487/04 (2006.01) ,C07D 498/04 (2006.01) ,C07D 513/04 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
471
Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/-C07D463/251
02
in which the condensed system contains two hetero rings
04
Ortho-condensed systems
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
487
Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/-C07D477/183
02
in which the condensed system contains two hetero rings
04
Ortho-condensed systems
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
498
Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
02
in which the condensed system contains two hetero rings
04
Ortho-condensed systems
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
513
Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/, C07D477/232
02
in which the condensed system contains two hetero rings
04
Ortho-condensed systems
Applicants: WACKER, Dean A.[US/US]; US (UsOnly)
ZHAO, Guohua[US/US]; US (UsOnly)
KWON, Chet[US/US]; US (UsOnly)
VARNES, Jeffrey G.[US/US]; US (UsOnly)
STEIN, Philip D.[US/US]; US (UsOnly)
BRISTOL-MYERS SQUIBB COMPANY[US/US]; Route 206 and Province Line Road Princeton, New Jersey 08543-4000, US (AllExceptUS)
Inventors: WACKER, Dean A.; US
ZHAO, Guohua; US
KWON, Chet; US
VARNES, Jeffrey G.; US
STEIN, Philip D.; US
Agent: DUNCAN, Sammy ; Bristol-Myers Squibb Company P.O. Box 4000 Princeton, New Jersey 08543-4000, US
Priority Data:
10/958,32505.10.2004US
60/509,43707.10.2003US
60/541,74604.02.2004US
Title (EN) MODULATORS OF SEROTONIN RECEPTORS
(FR) MODULATEURS DES RECEPTEURS DE LA SEROTONINE
Abstract:
(EN) The present invention provides modulators of serotonin receptors, pharmaceutical compositions containing such modulators and methods for treating various diseases, conditions and disorders associated with modulation of serotonin receptors such as, for example: metabolic diseases, which includes but is not limited to obesity, diabetes, diabetic complications, atherosclerosis, impared glucose tolerance and dyslipidemia; central nervous system diseases which includes but is not limited to, anxiety, depression, obsessive compulsive disorder, panic disorder, psychosis, schizophrenia, sleep disorder, sexual disorder and social phobias; cephalic pain; migraine; and gastrointestinal disorders using such compounds and compositions.
(FR) L'invention concerne des modulateurs des récepteurs de la sérotonine, des compositions pharmaceutiques renfermant de tels modulateurs et des méthodes de traitement de diverses maladies, états et troubles associés à la modulation des récepteurs de la sérotonine, tels que, par exemple: des maladies du métabolisme, notamment mais sans caractère restrictif, l'obésité, les diabètes, des complications diabétiques, l'athérosclérose, une diminution de tolérance au glucose et la dyslipidémie; des maladies du système nerveux central, notamment mais sans caractère restrictif, l'anxiété, la dépression, un trouble obsessionnel compulsif, un trouble panique, la psychose, la schizophrénie, un trouble du sommeil, un trouble sexuel et des phobies sociales; des douleurs céphaliques; la migraine; et des troubles gastro-intestinaux, au moyen de tels composés et compositions.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)