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1. (WO2005034955) SUBSTITUTED QUINOLINES AS PROTEIN TYROSINE KINASE ENZYME INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/034955    International Application No.:    PCT/US2003/032612
Publication Date: 21.04.2005 International Filing Date: 15.10.2003
IPC:
C07D 215/54 (2006.01), C07D 401/12 (2006.01), C07D 405/12 (2006.01), C07D 409/12 (2006.01), C07D 413/12 (2006.01), C07D 417/12 (2006.01)
Applicants: WYETH [US/US]; a corporation of the State of Delaware, Five Giralda Farms, Madison, NJ 07940 (US) (For All Designated States Except US).
WISSNER, Allan [US/US]; (US) (For US Only).
RABINDRAN, Sridhar, Krishna [IN/US]; (US) (For US Only).
TSOU, Hwei-Ru [US/US]; (US) (For US Only)
Inventors: WISSNER, Allan; (US).
RABINDRAN, Sridhar, Krishna; (US).
TSOU, Hwei-Ru; (US)
Agent: GOUDIE, Joy, S.; Wyeth, Patent Law Department, Five Giralda Farms, Madison, NJ 07940 (US)
Priority Data:
10/662,273 15.09.2003 US
Title (EN) SUBSTITUTED QUINOLINES AS PROTEIN TYROSINE KINASE ENZYME INHIBITORS
(FR) UTILISATION DE QUINOLINES SUBSTITUEES COMME INHIBITEURS DE LA TYROSINE KINASE
Abstract: front page image
(EN)This invention provides compounds of formula (I), having the structure wherein R1, R2, R3 are described within the specification. The compounds act as anti-cancer agents by inhibition of HER-2 and EGFR.
(FR)La présente invention concerne des composés représentés par la formule (1), présentant la structure (I), dans laquelle R1, R2 et R3 désignent des éléments décrits dans la partie descriptive de la présente demande. Ces composés agissent comme des agents anticancéreux et inhibent HER-2 et EGFR.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)