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Machine translation
1. (WO2005034844) EXOSITE-DIRECTED THROMBIN INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/034844    International Application No.:    PCT/US2004/021487
Publication Date: 21.04.2005 International Filing Date: 01.07.2004
Chapter 2 Demand Filed:    12.04.2005    
IPC:
A61K 38/00 (2006.01), A61K 38/36 (2006.01), C07K 4/12 (2006.01), C07K 14/745 (2006.01)
Applicants: CLEVELAND STATE UNIVERSITY [US/US]; 2121 Euclid Avenue, Cleveland, OH 44115 (US) (For All Designated States Except US).
KALAFATIS, Michael [US/US]; (US) (For US Only)
Inventors: KALAFATIS, Michael; (US)
Agent: BANDY, Mark, E.; Fay, Sharpe, Fagan, Minnich & McKee, LLP, 1100 Superior Avenue, Suite 700, Cleveland, OH 44114 (US)
Priority Data:
60/502,186 12.09.2003 US
Title (EN) EXOSITE-DIRECTED THROMBIN INHIBITORS
(FR) INHIBITEURS DE THROMBINE DIRIGES SUR DES EXOSITES
Abstract: front page image
(EN)Disclosed are an amino acid sequence of the human blood clotting factor Va, peptides containing such sequence, and additional peptides of interest that significantly inhibit thrombin generation. Also disclosed are pharmaceutical compositions containing these peptides and related therapeutic methods for inhibiting thrombin generation and treating blood coagulation disorders.
(FR)L'invention concerne une séquence d'acides aminés du facteur humain Va de coagulation du sang, des peptides contenant ces séquences et des peptides d'intérêt supplémentaires qui inhibent sensiblement la génération de thrombine. Elle concerne aussi des compositions pharmaceutiques contenant ces peptides et des procédés thérapeutiques correspondants pour inhiber la génération de thrombine et traiter les troubles de coagulation du sang.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)