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Machine translation
1. (WO2005033146) ATTACHMENT OF CELLS TO SURFACES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/033146    International Application No.:    PCT/SE2004/001414
Publication Date: 14.04.2005 International Filing Date: 05.10.2004
Chapter 2 Demand Filed:    15.04.2005    
IPC:
C07K 17/02 (2006.01), C12N 5/00 (2006.01)
Applicants: GE HEALTHCARE BIO-SCIENCES AB [SE/SE]; Björkgatan 30, S-751 84 Uppsala (SE) (For All Designated States Except US).
VAN ALSTINE, James [CA/SE]; (SE) (For US Only).
BERG, Hans [SE/SE]; (SE) (For US Only).
BJURLING, Åsa [SE/SE]; (SE) (For US Only)
Inventors: VAN ALSTINE, James; (SE).
BERG, Hans; (SE).
BJURLING, Åsa; (SE)
Agent: GE HEALTHCARE BIO-SCIENCES AB; Patents Department, Björkgatan 30, S-751 84 Uppsala (SE)
Priority Data:
0302652-3 06.10.2003 SE
Title (EN) ATTACHMENT OF CELLS TO SURFACES
(FR) FIXATION DE CELLULES A DES SURFACES
Abstract: front page image
(EN)The present invention relates to a microcarrier onto the surface of which a cationic compound has been immobilised via a guanidine group. The microcarrier is capable of attachment of cells, e.g. via charge-based interaction, and is advantageously used as a support in the culture of cells. Said compound may comprise one or two amino acids, such as arginine (Arg) or a dipeptide. The invention also relates to a method of preparing a polycationic microcarrier, which method comprises to immobilise a compound that comprises at least one guanidine group to an epoxide-activated substrate.
(FR)La présente invention concerne un microsupport à la surface duquel un composé cationique a été immobilisé via un groupe de guanidine. Le microsupport est capable d'assurer la fixation de cellules, par exemple, par l'interaction basée sur les charges, et peut s'utiliser avantageusement en tant que support dans la culture de cellules. Ce composé peut comprendre un ou deux acides aminés tels que l'arginine (Arg) ou un dipeptide. L'invention concerne aussi un procédé pour préparer un microsupport polycationique, ledit procédé consistant à immobiliser un composé qui comprend au moins un groupe de guanidine sur un support activé par époxyde.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)