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Machine translation
1. (WO2005032556) METHOD FOR REDUCING PAIN
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/032556    International Application No.:    PCT/US2004/032559
Publication Date: 14.04.2005 International Filing Date: 01.10.2004
Chapter 2 Demand Filed:    15.04.2005    
IPC:
A61K 31/195 (2006.01), A61K 31/4168 (2006.01), A61K 31/445 (2006.01), A61K 31/4468 (2006.01), A61K 31/4535 (2006.01), A61K 31/485 (2006.01), A61K 38/17 (2006.01), A61K 45/06 (2006.01)
Applicants: ELAN PHARMACEUTICALS, INC. [US/US]; 800 Gateway Boulevard, South San Francisco, CA 94080 (US) (For All Designated States Except US).
ELLIS, David, J. [US/US]; (US) (For US Only).
MILJANICH, George [US/US]; (US) (For US Only).
SHIELDS, David [US/US]; (US) (For US Only)
Inventors: ELLIS, David, J.; (US).
MILJANICH, George; (US).
SHIELDS, David; (US)
Agent: KUNG, Viola, T.; 2941 Fairview Park Drive, Box 7, Falls Church, VA 22042 (US)
Priority Data:
60/508,625 02.10.2003 US
60/508,469 03.10.2003 US
Title (EN) METHOD FOR REDUCING PAIN
(FR) METHODE DE SOULAGEMENT DE LA DOULEUR
Abstract: front page image
(EN)The present invention is direct to a method of producing analgesia in a mammalian subject. The method includes administering to the subject an omega conopeptide, preferably ziconotide, in combination with an analgesic selected from the group consisting of morphine, bupivicaine, clonidine, hydromorphone, baclofen, fentanyil, buprenorphine, and sufentanil, or its pharmaceutically acceptable salts thereof, wherein the ω-conopeptide retains its potency and is physically and chemically compatible with the analgesic compound. A preferred route of administration is intrathecal administration, particularly continuous intrathecal infusion. The present invention is also directed to a pharmaceutical formulation comprising an omega conopeptide, preferably ziconotide, in combination with an analgesic selected from the group consisting of morphine, bupivicaine, clonidine, hydromorphone, baclofen, fentanyl, buprenorphine, and sufentanil.
(FR)La présente invention concerne une méthode de génération d'une analgésie chez un sujet mammalien. Cette méthode consiste à administrer au sujet un $g(v)-conopeptide, de préférence, le ziconotide mélangé à un analgésique sélectionné parmi le groupe englobant la morphine, la bupivacaïne, la clonidine, l'hydromorphone, le baclofen, le fentanyil, la buprénorphine et le sufentanil, ou ses sels acceptables pharmaceutiquement, l'$g(v)-conopeptide gardant sa puissance et étant physiquement et chimiquement compatible au composé analgésique. Une voie d'administration préférée est l'administration intrathécale, notamment, la perfusion intrathécale. Cette invention a aussi pour objet une préparation pharmaceutique contenant un $g(v)-conopeptide, de préférence, le ziconotide mélangé à un analgésique sélectionné parmi le groupe englobant la morphine, la bupivacaïne, la clonidine, l'hydromorphone, le baclofen, le fentanyil, la buprénorphine et le sufentanil.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)