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1. (WO2005032534) OPHTHALMIC COMPOSITION FOR TREATING LACRIMAL DISORDERS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2005/032534 International Application No.: PCT/JP2004/014774
Publication Date: 14.04.2005 International Filing Date: 30.09.2004
IPC:
A61K 31/19 (2006.01)
Applicants: UMEDA, Yuzuru[JP/JP]; JP (UsOnly)
NAKASHIMA, Hideo[JP/JP]; JP (UsOnly)
SHIBUYA, Michiko[JP/JP]; JP (UsOnly)
SAITOH, Yasukazu[JP/JP]; JP (UsOnly)
OKADA, Shoji[JP/JP]; JP (UsOnly)
NAKAMURA, Shigeru[JP/JP]; JP (UsOnly)
OPHTECS CORPORATION[JP/JP]; 9-1, Edobori 1-chome Nishi-ku, Osaka-shi Osaka 550-0002, JP (AllExceptUS)
Inventors: UMEDA, Yuzuru; JP
NAKASHIMA, Hideo; JP
SHIBUYA, Michiko; JP
SAITOH, Yasukazu; JP
OKADA, Shoji; JP
NAKAMURA, Shigeru; JP
Agent: OHSHIMA, Masataka; Ohshima Patent Office BN Gyoen Building 17-11, Shinjuku 1-chome Shinjuku-ku, Tokyo 160-0022, JP
Priority Data:
2003-34685806.10.2003JP
Title (EN) OPHTHALMIC COMPOSITION FOR TREATING LACRIMAL DISORDERS
(FR) COMPOSITION OPHTALMIQUE POUR LE TRAITEMENT DES TROUBLES LACRYMAUX
(JA) 涙液異常の治療のための眼科用組成物
Abstract:
(EN) It is intended to provide an ophthalmic composition characterized by containing 3-hydroxybutyric acid and/or its salt as the active ingredient(s) and being used for preventing eyes from dryness and, in its turn, an ophthalmic composition characterized by being used for treating lacrimal disorders. By using the above ophthalmic composition, eyes can be prevented from dryness and, in its turn, lacrimal disorders can be treated. Thus, use of the composition makes it possible to ameliorate unpleasant symptoms caused by lacrimal disorders such as eye dryness, foreign-body sensation, eye unpleasantness and eye fatigue. Moreover, this ophthalmic composition can prevent the onset of diseases caused by lacrimal disorders such as dry eye and suspected cases of dry eye. More specifically speaking, it can prevent the onset of diseases caused by lacrimal disorders without injuring cornea or conjunctiva.
(FR) L'invention concerne une composition ophtalmique caractérisée en ce qu'elle contient de l'acide 3-hydroxybutyrique et/ou son sel en tant que principe(s) actif(s), qui est destinée à empêcher la sécheresse des yeux et s'utilise par la même pour le traitement des troubles lacrymaux. Cette composition permet d d'atténuer des symptômes désagréables provoqués par des troubles lacrymaux tels que sécheresse oculaire, sensation de présence d'un corps étranger, désagrément oculaire, fatigue de l'oeil. De plus, cette composition ophtalmique peut empêcher l'apparition de maladies provoquées par des troubles lacrymaux telles que sécheresse de l'oeil avérée ou présumée. Plus précisément, cette composition peut empêcher l'apparition de maladies dues à des troubles lacrymaux sans lésion de la cornée ou de la conjonctive.
(JA) 3-ヒドロキシ酪酸および/またはその塩を有効成分として含有し、そして、眼の乾燥抑制のために用いられることを特徴とする眼科用組成物、ひいては、涙液異常の治療のために用いられることを特徴とする眼科用組成物を提供する。本発明の眼科用組成物を用いることにより、眼の乾燥を抑制することができ、ひいては、涙液異常の治療ができる。それゆえ、該組成物を用いることにより、眼の乾燥をはじめ、異物感、眼の不快感および眼の疲れ等の涙液異常による不快症状等を改善することができる。さらには、本発明の眼科用組成物は、涙液異常により発症する疾患、例えば、眼の乾燥に関連する障害であるドライアイおよびドライアイ疑い例の発症を抑制すること、特には、角結膜に障害を伴わず且つ涙液異常により発症する疾患の発症を抑制することができる。
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)