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Machine translation
1. (WO2005032523) INJECTABLE, ORAL, OR TOPICAL SUSTAINED RELEASE PHARMACEUTICAL FORMULATIONS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/032523    International Application No.:    PCT/US2004/031570
Publication Date: 14.04.2005 International Filing Date: 27.09.2004
Chapter 2 Demand Filed:    28.07.2005    
IPC:
A61K 9/16 (2006.01)
Applicants: ACUSPHERE, INC. [US/US]; 500 Arsenal Street, Watertown, MA 02472 (US) (For All Designated States Except US).
BERNSTEIN, Howard [CA/US]; (US) (For US Only).
CHICKERING, Donald, E., III [US/US]; (US) (For US Only).
HUANG, Eric, K. [US/US]; (US) (For US Only).
NARASIMHAN, Sridhar [IN/US]; (US) (For US Only).
REESE, Shaina [US/US]; (US) (For US Only).
STRAUB, Julie, A. [US/US]; (US) (For US Only)
Inventors: BERNSTEIN, Howard; (US).
CHICKERING, Donald, E., III; (US).
HUANG, Eric, K.; (US).
NARASIMHAN, Sridhar; (US).
REESE, Shaina; (US).
STRAUB, Julie, A.; (US)
Agent: KING, Kevin, W.; Sutherland Asbill & Brennan LLP, 999 Peachtree Street, NE, Atlanta, GA 30309-3996 (US)
Priority Data:
60/507,384 30.09.2003 US
Title (EN) INJECTABLE, ORAL, OR TOPICAL SUSTAINED RELEASE PHARMACEUTICAL FORMULATIONS
(FR) FORMULATIONS PHARMACEUTIQUES A EFFET PROLONGE, ADMINISTREES PAR INJECTION, PAR VOIE ORALE OU TOPIQUE
Abstract: front page image
(EN)Pharmaceutical formulations and methods are provided for the sustained delivery of a pharmaceutical agent to a patient by injection, by oral administration or by topical administration. The injectable formulation includes porous microparticles which comprise a pharmaceutical agent and a matrix material, wherein upon injection of the formulation a therapeutically or prophylactically effective amount of the pharmaceutical agent is released from the microparticles for at least 24 hours. The oral formulation includes porous microparticles which comprise a pharmaceutical agent and a matrix material, wherein a therapeutically or prophylactically effective amount of the pharmaceutical agent is released from the microparticles for at least 2 hours following oral administration. The topical formulation includes porous microparticles which comprise a pharmaceutical agent and a matrix material, wherein a therapeutically or prophylactically effective amount of the pharmaceutical agent is released from the microparticles for at least 2 hours following topical administration.
(FR)L'invention concerne des formulations pharmaceutiques et des méthodes pour l'administration à effet prolongé d'un agent pharmaceutique à un patient par injection, ou bien par voie orale ou topique. La formulation injectable comporte des microparticules poreuses contenant un agent pharmaceutique et une matrice. Après injection de la formulation, une quantité thérapeutiquement ou prophylactiquement efficace de l'agent pharmaceutique est libérée des microparticules pendant au moins 24 heures. La formulation orale comprend des microparticules poreuses contenant un agent pharmaceutique et une matrice, une quantité thérapeutiquement ou prophylactiquement efficace de l'agent pharmaceutique étant libérée des microparticules pendant au moins 2 heures après la prise par voie orale. La formulation topique comprend des microparticules poreuses contenant un agent pharmaceutique et une matrice, une quantité thérapeutiquement ou prophylactiquement efficace de l'agent pharmaceutique étant libérée des microparticules pendant au moins 2 heures après la prise par voie topique.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)