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1. (WO2005032515) NEW USE, PHARMACEUTICAL PREPARATIONS AS WELL AS A PROCESS FOR THEIR PRODUCTION
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2005/032515 International Application No.: PCT/US2004/031650
Publication Date: 14.04.2005 International Filing Date: 28.09.2004
IPC:
A61K 9/08 (2006.01) ,A61K 9/19 (2006.01) ,A61K 31/185 (2006.01) ,A61K 31/675 (2006.01) ,A61K 45/06 (2006.01) ,A61K 47/20 (2006.01) ,A61K 47/26 (2006.01)
Applicants: ROESSLER, Berthold[--/US]; US (UsOnly)
BAXTER INTERNATIONAL INC.[US/US]; One Baxter Parkway Deerfield, IL 60015, US (AllExceptUS)
BAXTER HEALTHCARE S.A.[CH/CH]; Hertistrasse 2 Wallisellen Kanton CH-8306 Zurich, CH (AllExceptUS)
Inventors: ROESSLER, Berthold; US
Agent: MAYO, Michael, C. ; Baxter International Inc. One Baxter Parkway Deerfield, IL 60015, US
Priority Data:
60/507,75001.10.2003US
Title (EN) NEW USE, PHARMACEUTICAL PREPARATIONS AS WELL AS A PROCESS FOR THEIR PRODUCTION
(FR) NOUVELLE UTILISATION, PREPARATIONS PHARMACEUTIQUES ET PROCEDE POUR LEUR PRODUCTION
Abstract:
(EN) The invention concerns the use of mercaptoethane sulfonate-sodium (Mesna) to increase the solubility of the Ifosfamide in storage-stable, concentrated and/or highly-concentrated (supersaturated) aqueous pharmaceutical Ifosfamide preparations for parenteral administration as well as a process for their production.
(FR) L'invention concerne l'utilisation d'un mercaptoéthane sulfonate de sodium (Mesna) pour augmenter la solubilité de l'ifosfamide dans des préparations pharmaceutiques d'ifosfamide aqueuses concentrées et/ou hautement concentrées (sursaturées) stables au stockage destinées à une administration parentérale, ainsi qu'un procédé pour leur production.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)