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1. (WO2005030794) HEMIASTERLIN DERIVATIVES AND USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/030794    International Application No.:    PCT/US2004/030921
Publication Date: 07.04.2005 International Filing Date: 22.09.2004
IPC:
A61K 31/395 (2006.01), A61K 38/04 (2006.01), A61K 38/05 (2006.01), C07K 1/06 (2006.01), C07K 5/00 (2006.01), C07K 5/04 (2006.01), C07K 5/06 (2006.01)
Applicants: EISAI CO. LTD. [JP/JP]; 6-10 Koishikawa 4-Chrome, Bunkyo-ku, Tokyo 112-8088 (JP) (For All Designated States Except US).
KOWALCZYK, James, J. [US/US]; (US) (For US Only).
SCHILLER, Shawn [US/US]; (US) (For US Only).
SELETSKY, Boris, M. [US/US]; (US) (For US Only).
SPYVEE, Mark [GB/US]; (US) (For US Only).
YANG, Hu [US/US]; (US) (For US Only).
CAMPAGNA, Silvio, A. [US/US]; (US) (For US Only).
FANG, Francis, G. [US/US]; (US) (For US Only)
Inventors: KOWALCZYK, James, J.; (US).
SCHILLER, Shawn; (US).
SELETSKY, Boris, M.; (US).
SPYVEE, Mark; (US).
YANG, Hu; (US).
CAMPAGNA, Silvio, A.; (US).
FANG, Francis, G.; (US)
Agent: LAGNEAU, Nadège, M.; Patent Group, Choate, Hall & Stewart LLP, Two International Place, Boston, MA 02110 (US)
Priority Data:
10/667,864 22.09.2003 US
Title (EN) HEMIASTERLIN DERIVATIVES AND USES THEREOF
(FR) DERIVES D'HEMIASTERLINE ET UTILISATIONS DE CES DERIVES
Abstract: front page image
(EN)The present invention provides compounds having formula (I): and additionally provides methods for the synthesis thereof and methods for the use thereof in the treatment of cancer, wherein R1-R7, X1, X2, R, Q, and n are as defined herein.
(FR)La présente invention concerne des composés de formule (I) ainsi que des procédés de synthèse et des procédés d'utilisation de ces composés dans le traitement du cancer. Dans cette formule, R1-R7, X1, X2, R, Q et n sont tels que définis dans la description.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)