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1. (WO2005030726) ISOQUINOLINONE POTASSIUM CHANNEL INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2005/030726 International Application No.: PCT/US2004/030484
Publication Date: 07.04.2005 International Filing Date: 17.09.2004
IPC:
C07D 217/24 (2006.01) ,C07D 401/04 (2006.01) ,C07D 401/06 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
217
Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
22
with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
24
Oxygen atoms
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
401
Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
02
containing two hetero rings
04
directly linked by a ring-member-to-ring- member bond
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
401
Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
02
containing two hetero rings
06
linked by a carbon chain containing only aliphatic carbon atoms
Applicants: DINSMORE, Christopher, J.[US/US]; US (UsOnly)
BERGMAN, Jeffrey, M.[US/US]; US (UsOnly)
MCINTYRE, Charles, J.[US/US]; US (UsOnly)
ISAACS, Richard[US/US]; US (UsOnly)
CLAREMON, David, A.[US/US]; US (UsOnly)
MERCK & CO., INC.[US/US]; 126 East Lincoln Avenue Rahway, New Jersey 07065-0907, US (AllExceptUS)
Inventors: DINSMORE, Christopher, J.; US
BERGMAN, Jeffrey, M.; US
MCINTYRE, Charles, J.; US
ISAACS, Richard; US
CLAREMON, David, A.; US
Common
Representative:
MERCK & CO., INC.; 126 East Lincoln Avenue Rahway, New Jersey 07065-0907, US
Priority Data:
60/505,21523.09.2003US
Title (EN) ISOQUINOLINONE POTASSIUM CHANNEL INHIBITORS
(FR) INHIBITEURS DU CANAL POTASSIQUE A BASE D'ISOQUINOLINONE
Abstract:
(EN) The present invention relates to compounds having the structure (I) useful as potassium channel inhibitors to treat cardiac arrhythmias, and the like.
(FR) La présente invention concerne des composés de structure (I) utiles comme inhibiteurs du canal potassique pour traiter les arythmies cardiaques et analogues.
front page image
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)