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1. (WO2005030185) METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2005/030185 International Application No.: PCT/JP2004/014428
Publication Date: 07.04.2005 International Filing Date: 24.09.2004
IPC:
A61K 31/00 (2006.01) ,A61K 31/137 (2006.01) ,A61K 31/16 (2006.01) ,A61K 31/165 (2006.01) ,A61K 31/167 (2006.01) ,A61K 31/27 (2006.01) ,A61K 31/41 (2006.01) ,A61K 31/4196 (2006.01) ,A61K 31/47 (2006.01)
Applicants: OKAMOTO, Hiroshi[JP/JP]; JP (UsOnly)
FURUKAWA, Noboru[JP/JP]; JP (UsOnly)
SASASE, Tomohiko[JP/JP]; JP (UsOnly)
JAPAN TOBACCO INC.[JP/JP]; 2-1, Toranomon 2-chome Minato-ku Tokyo 105-8422, JP (AllExceptUS)
Inventors: OKAMOTO, Hiroshi; JP
FURUKAWA, Noboru; JP
SASASE, Tomohiko; JP
Agent: DAITO, Teruo; 2nd FI, Kyowa Kogyo Bldg. 21-40 Takanawa 2-chome Minato-ku, Tokyo 108-0074, JP
Priority Data:
2003-37345326.09.2003JP
60/590,81123.07.2004US
Title (EN) METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION
(FR) PROCEDE POUR INHIBER LA PRODUCTION DE LIPOPROTEINES RESTANTES
Abstract:
(EN) The present invention aims to provide for the treatment of hyperlipidemia, arteriosclerosis and hyper-remnant-emia, and to inhibit remnant lipoportein production by adminsetering an inhibitor of CEPT (cholesteryl ester transfer protein). Said inhibitor is a compound selected from the group cosisting of compounds of formula I to fomula XXIII, and compounds selected from the group consisting of JTT-705, CP-529414, SC-795, SC-744, SC-554, SC-71952, SC-56960, SC-57201, PD-140195, WK-5341A, WK-5344B, CETI-1 (CETP Vaccine), BM99-1 and BM99-2.
(FR) L'objectif de la présente invention est de fournir un procédé pour inhiber la production de lipoprotéines restantes et un inhibiteur de production de lipoprotéines restantes, lequel procédé consiste à administrer un composé possédant une activité inhibitrice de la CETP à un sujet. L'inhibiteur de production de lipoprotéines restantes selon la présente invention contient comme principe actif un composé possédant une activité inhibitrice de la CETP.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)