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1. (WO2005030040) HEMATOPOIETIC STEM CELL IDENTIFICATION AND ISOLATION
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2005/030040 International Application No.: PCT/US2004/031677
Publication Date: 07.04.2005 International Filing Date: 27.09.2004
IPC:
C12N 5/00 (2006.01) ,G01N 33/567 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5
Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
566
using specific carrier or receptor proteins as ligand binding reagent
567
utilising isolate of tissue or organ as binding agent
Applicants:
YILMAZ, Omer, H. [US/US]; US (UsOnly)
KIEL, Mark, J. [US/US]; US (UsOnly)
MORRISON, Sean [US/US]; US (UsOnly)
IWASHITA, Toshihide [JP/US]; US (UsOnly)
THE REGENTS OF THE UNIVERSITY OF MICHIGAN [US/US]; 3003 South State Street Ann Arbor, MI 48109-1280, US (AllExceptUS)
Inventors:
YILMAZ, Omer, H.; US
KIEL, Mark, J.; US
MORRISON, Sean; US
IWASHITA, Toshihide; US
Agent:
BOND, Jason, R. ; Medlen & Carroll, LLP 101 Howard Street Suite 350 San Francisco, CA 94105, US
Priority Data:
60/506,11126.09.2003US
null27.09.2004US (Considered void 30.08.2005)
Title (EN) HEMATOPOIETIC STEM CELL IDENTIFICATION AND ISOLATION
(FR) IDENTIFICATION ET ISOLATION DE CELLULES SOUCHES HEMATOPOIETIQUES
Abstract:
(EN) The present invention relates to methods of identifying, collecting and isolating hematopoietic stem cells (HSCs) and compositions of purified HSCs. Specifically, the present invention provides methods of isolating and purifying CD150+ HSCs, CD48- HSCs, andCD244- HSCs. The present invention also relates to purified cell samples with enriched CD 150+ HSCs, CD48' HSCs, andCD244' HSCs populations, as well as methods of treating subjects with such compositions.
(FR) La présente invention concerne des techniques d'identification, de collecte et d'isolement de cellules souches hématopoïétiques (HSC) et des composition de cellules HCS purifiées. Cette invention concerne en particulier des techniques d'isolement et de purification de cellules HCS CD150+, HCS CD48 et HCS D244. Cette invention concerne aussi des échantillons de cellules purifiées avec des populations de cellules HSC CD 150+, HSC CD48', et HSC CD244', ainsi que des techniques de traitement de sujets avec ces compositions.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)