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1. (WO2005030040) HEMATOPOIETIC STEM CELL IDENTIFICATION AND ISOLATION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/030040    International Application No.:    PCT/US2004/031677
Publication Date: 07.04.2005 International Filing Date: 27.09.2004
IPC:
C12N 5/00 (2006.01), G01N 33/567 (2006.01)
Applicants: THE REGENTS OF THE UNIVERSITY OF MICHIGAN [US/US]; 3003 South State Street, Ann Arbor, MI 48109-1280 (US) (For All Designated States Except US).
YILMAZ, Omer, H. [US/US]; (US) (For US Only).
KIEL, Mark, J. [US/US]; (US) (For US Only).
MORRISON, Sean [US/US]; (US) (For US Only).
IWASHITA, Toshihide [JP/US]; (US) (For US Only)
Inventors: YILMAZ, Omer, H.; (US).
KIEL, Mark, J.; (US).
MORRISON, Sean; (US).
IWASHITA, Toshihide; (US)
Agent: BOND, Jason, R.; Medlen & Carroll, LLP, 101 Howard Street, Suite 350, San Francisco, CA 94105 (US)
Priority Data:
60/506,111 26.09.2003 US
  27.09.2004 US (Considered void 30.08.2005)
Title (EN) HEMATOPOIETIC STEM CELL IDENTIFICATION AND ISOLATION
(FR) IDENTIFICATION ET ISOLATION DE CELLULES SOUCHES HEMATOPOIETIQUES
Abstract: front page image
(EN)The present invention relates to methods of identifying, collecting and isolating hematopoietic stem cells (HSCs) and compositions of purified HSCs. Specifically, the present invention provides methods of isolating and purifying CD150+ HSCs, CD48- HSCs, andCD244- HSCs. The present invention also relates to purified cell samples with enriched CD 150+ HSCs, CD48' HSCs, andCD244' HSCs populations, as well as methods of treating subjects with such compositions.
(FR)La présente invention concerne des techniques d'identification, de collecte et d'isolement de cellules souches hématopoïétiques (HSC) et des composition de cellules HCS purifiées. Cette invention concerne en particulier des techniques d'isolement et de purification de cellules HCS CD150+, HCS CD48 et HCS D244. Cette invention concerne aussi des échantillons de cellules purifiées avec des populations de cellules HSC CD 150+, HSC CD48', et HSC CD244', ainsi que des techniques de traitement de sujets avec ces compositions.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)