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1. (WO2005027994) APPLICATION OF A THERAPEUTIC SUBSTANCE TO A TISSUE LOCATION USING A POROUS MEDICAL DEVICE
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2005/027994 International Application No.: PCT/US2004/030173
Publication Date: 31.03.2005 International Filing Date: 15.09.2004
IPC:
A61M 5/32 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
M
DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
5
Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
178
Syringes
31
Details
32
Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
Applicants:
ATRIUM MEDICAL CORPORATION [US/US]; 5 Wentworth Drive Hudson, NH 03051, US (AllExceptUS)
HERWECK, Steve, A. [US/US]; US (UsOnly)
MARTAKOS, Paul [US/US]; US (UsOnly)
MOODIE, Geoffrey [US/US]; US (UsOnly)
LABRECQUE, Roger [US/US]; US (UsOnly)
KARWOSKI, Theodore [US/US]; US (UsOnly)
CARLTON, Trevor [US/US]; US (UsOnly)
Inventors:
HERWECK, Steve, A.; US
MARTAKOS, Paul; US
MOODIE, Geoffrey; US
LABRECQUE, Roger; US
KARWOSKI, Theodore; US
CARLTON, Trevor; US
Agent:
CANNING, Kevin, J. ; Lahive & Cockfield, LLP 28 State Street Boston, MA 02109, US
Priority Data:
60/503,35715.09.2003US
Title (EN) APPLICATION OF A THERAPEUTIC SUBSTANCE TO A TISSUE LOCATION USING A POROUS MEDICAL DEVICE
(FR) APPLICATION D'UNE SUBSTANCE THERAPEUTIQUE DANS UN EMPLACEMENT TISSULAIRE AU MOYEN D'UN DISPOSITIF MEDICAL POREUX
Abstract:
(EN) A non-polymeric or biological coating applied to porous radially expandable interventional medical devices provides uniform drug distribution and permeation of the coating and any therapeutic agents mixed therewith into a targeted treatment area within the body. The coating is sterile, and is capable of being carried by a sterile medical device to a targeted tissue location within the body following radial expansion. The therapeutic coating transfers off the medical device due in part to a biological attraction with the tissue and in part to a physical transference from the medical device to the targeted tissue location in contact with the medical device. Thus, atraumatic local tissue transference delivery is achieved for uniform therapeutic agent distribution and controlled bio-absorption into the tissue after placement within a patient's body with a non-inflammatory coating.
(FR) L'invention concerne un revêtement non polymère ou biologique appliqué sur des dispositifs médicaux d'intervention poreux à expansion radiale permettant de distribuer un médicament de manière uniforme et d'obtenir une perméabilité du revêtement et des agents thérapeutiques quelconques mélangés avec celui-ci dans une zone de traitement ciblée dans un corps. Le revêtement est stérile et peut être transporté au moyen d'un dispositif médical stérile dans un emplacement tissulaire ciblé dans le corps suite à l'expansion radiale du dispositif. Le revêtement thérapeutique transfère le dispositif médical partiellement en raison d'une attraction biologique avec le tissu et partiellement en raison d'un transfert physique du dispositif médical à l'emplacement tissulaire ciblé en contact avec le dispositif médical. Par conséquent, une administration de transfert tissulaire local atraumatique est obtenue pour une distribution d'agents thérapeutiques uniforme et une bio-absorption commandée dans le tissu, après le placement dans le corps d'un patient au moyen d'un revêtement non inflammatoire.
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Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP1663345JP2007505655