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Machine translation
1. (WO2005017118) SULFS AS MODIFIERS OF THE BETA CATENIN PATHWAY AND METHODS OF USE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/017118    International Application No.:    PCT/US2004/026338
Publication Date: 24.02.2005 International Filing Date: 12.08.2004
IPC:
C07K 16/40 (2006.01), C12Q 1/00 (2006.01)
Applicants: EXELIXIS, INC. [US/US]; 170 Harbor Way, P.O. Box 511, South San Francisco, California 94083-0511 (US) (For All Designated States Except US).
FRANCIS-LANG, Helen [GB/US]; (US) (For US Only).
WINTER, Christopher G. [US/US]; (US) (For US Only).
VENTURA, Richard Benn Abegania [US/US]; (US) (For US Only).
HEUER, Timothy S. [US/US]; (US) (For US Only).
ZHANG, HaiGuang [US/US]; (US) (For US Only)
Inventors: FRANCIS-LANG, Helen; (US).
WINTER, Christopher G.; (US).
VENTURA, Richard Benn Abegania; (US).
HEUER, Timothy S.; (US).
ZHANG, HaiGuang; (US)
Agent: SHAYESTEH, Laleh; 170 Harbor Way, P.O. Box 511, South San Francisco, CA 94083-0511 (US)
Priority Data:
60/495,172 14.08.2003 US
Title (EN) SULFS AS MODIFIERS OF THE BETA CATENIN PATHWAY AND METHODS OF USE
(FR) SULF UTILISES COMME MODIFICATEURS DE LA VOIE BETA-CATENINE ET PROCEDES ASSOCIES
Abstract: front page image
(EN)Human SULF genes are identified as modulators of the beta catenin pathway, and thus are therapeutic targets for disorders associated with defective beta catenin function. Methods for identifying modulators of beta catenin, comprising screening for agents that modulate the activity of SULF are provided.
(FR)L'invention concerne des gènes SULF humains identifiés comme modulateurs de la voie bêta-caténine, qui constituent par conséquent des cibles thérapeutiques pour les troubles liés à une fonction bêta-caténine déficiente. L'invention concerne en outre des procédés d'identification de modulateurs de la bêta-caténine, notamment des procédés de criblage d'agents modulant l'activité des SULF.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)