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Machine translation
1. (WO2005016255) SUBSTITUTED TETRAHYDROQUINOLINES, PHENYLACETIC ACIDS AND BENZOIC ACIDS AS HEPATOCYTE NUCLEAR FACTOR 4 (HNF-4 ) MODULATOR COMPOUNDS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/016255    International Application No.:    PCT/US2004/023093
Publication Date: 24.02.2005 International Filing Date: 16.07.2004
IPC:
A61K 31/4741 (2006.01), A61K 31/4743 (2006.01), A61K 31/4745 (2006.01), A61K 31/55 (2006.01), A61P 3/00 (2006.01), C07D 471/04 (2006.01), C07D 491/048 (2006.01), C07D 491/052 (2006.01), C07D 495/04 (2006.01)
Applicants: LIGAND PHARMACEUTICALS INCORPORATED [US/US]; 10275 Science Center Drive, San Diego, CA 92121 (US) (For All Designated States Except US).
MICHELLYS, Pierre [FR/US]; (US) (For US Only).
CHEN, Jyun-Hung [--/US]; (US) (For US Only).
MEYER, Hoyt [US/US]; (US) (For US Only).
KARANEWSKY, Donald [US/US]; (US) (For US Only)
Inventors: MICHELLYS, Pierre; (US).
CHEN, Jyun-Hung; (US).
MEYER, Hoyt; (US).
KARANEWSKY, Donald; (US)
Agent: SEIDMAN, Stephanie, L.; Fish & Richardson P.C., 12390 El Camino Real, San Diego, CA 92130 (US)
Priority Data:
60/488,071 16.07.2003 US
Title (EN) SUBSTITUTED TETRAHYDROQUINOLINES, PHENYLACETIC ACIDS AND BENZOIC ACIDS AS HEPATOCYTE NUCLEAR FACTOR 4 (HNF-4 ) MODULATOR COMPOUNDS
(FR) TETRAHYDROQUINOLINES A SUBSTITUTION, ACIDES PHENYLACETIQUES ET BENZOIQUES, COMME COMPOSES MODULATEURS DE RECEPTEUR DU FACTEUR NUCLEAIRE D'HEPATOCYTE 4$G(A) (HNF-4$G(A) )
Abstract: front page image
(EN)This invention relates to substituted tetrahydroquinoline phenylacetic acids and benzoic acids that bind to and/or modulate hepatocyte factor 4&agr; receptors and to methods for making and using such compounds.
(FR)L'invention concerne des composés modulateurs de récepteur du facteur nucléaire d'hépatocyte 4$g(a) (HNF-4$g(a)), ainsi que des compositions pharmaceutiques renfermant ces composés et des procédés faisant appel aux composés et compositions pharmaceutiques en question pour la modulation des récepteurs du facteur HNF-4$g(a), et également des processus dont la médiation est assurée par les récepteurs considérés. L'invention concerne en outre des procédés relatifs à l'élaboration des composés et compositions pharmaceutiques en question, et des intermédiaires utilisés dans leur synthèse.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)