WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2005016244) METHODS AND COMPOSITIONS FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/016244    International Application No.:    PCT/US2004/018751
Publication Date: 24.02.2005 International Filing Date: 14.06.2004
IPC:
A61K 38/00 (2006.01), A61K 38/02 (2006.01), C07K 2/00 (2006.01), C07K 7/08 (2006.01)
Applicants: MICROBIA, INC. [US/US]; 320 Bent Street, Cambridge, MA 02141 (US) (For All Designated States Except US).
CURRIE, Mark, G. [US/US]; (US) (For US Only).
MAHAJAN-MIKLOS, Shalina [IN/US]; (US) (For US Only).
LI, Jing, Sun [US/US]; (US) (For US Only)
Inventors: CURRIE, Mark, G.; (US).
MAHAJAN-MIKLOS, Shalina; (US).
LI, Jing, Sun; (US)
Agent: MEIKLEJOHN, Anita, L.; Fish & Richardson P.C., 225 Franklin Street, Boston, MA 02110-2804 (US)
Priority Data:
60/478,492 13.06.2003 US
60/532,361 23.12.2003 US
60/571,386 14.05.2004 US
Title (EN) METHODS AND COMPOSITIONS FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS
(FR) METHODES ET COMPOSITIONS POUR LE TRAITEMENT DE TROUBLES GASTRO-INTESTINAUX
Abstract: front page image
(EN)Compositions and related methods for treating IBS and other gastrointestinal disorders and conditions (e.g., gastrointestinal motility disorders, functional gastrointestinal disorders, gastroesophageal reflux disease (GERD), duodenogastric reflux, Crohn's disease, ulcerative colitis, inflammatory bowel disease, functional heartburn, dyspepsia (including functional dyspepsia or nonulcer dyspepsia), gastroparesis, chronic intestinal pseudo-obstruction (or colonic pseudoobstruction), and disorders and conditions associated with constipation, e.g., constipation associated with use of opiate pain killers, post-surgical constipation, and constipation associated with neuropathic disorders as well as other conditions and disorders are described. The compositions feature peptides that activate the guanylate cyclase C (GC-C) receptor.
(FR)L'invention concerne des compositions et des méthodes associées pour traiter le syndrome du colon irritable et d'autres troubles gastro-intestinaux et pathologies associées, par exemple, des troubles de motilité gastro-intestinale, des troubles gastro-intestinaux fonctionnels, des maladies de reflux gastro-oesophagien (GERD), de reflux duodénogastrique, la maladie de Crohn, la colite ulcéreuse, une maladie intestinale inflammatoire, des aigreurs d'estomac fonctionnelles, une dyspepsie (notamment dyspepsie fonctionnelle ou dyspepsie non ulcéreuse), une gastroparèse, une pseudo-obstruction intestinale chronique (ou une pseudo-obstruction colonique), et des troubles et pathologies associés à la constipation, par exemple, constipation associée à l'utilisation de médicaments anti-douleurs opiacés, à la constipation post-chirurgicale, à la constipation associée à des troubles neuropathiques, ainsi qu'à d'autres troubles analogues. Les compositions comportent des peptides activant le récepteur de la guanylate cyclase C (GC-C).
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)