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1. (WO2005015218) USE OF PROTEINS PROTEINASE 3 (PRN3) AND LEUKOCYTE ELASTASE INHIBITOR (ILEU) AS A MARKER FOR COLORECTAL CANCER
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/015218    International Application No.:    PCT/EP2004/008082
Publication Date: 17.02.2005 International Filing Date: 20.07.2004
IPC:
G01N 33/574 (2006.01)
Applicants: ROCHE DIAGNOSTICS GMBH [DE/DE]; Sandhofer Strasse 116, 68305 Mannheim (DE) (DE only).
F. HOFFMANN-LA ROCHE AG [CH/CH]; Grenzacherstrasse 124, CH-4070 Basel (CH) (AE, AG, AL, AM, AT, AU, AZ, BA, BB, BE, BF, BG, BJ, BR, BW, BY, BZ, CA, CF, CG, CH, CI, CM, CN, CO, CR, CU, CY, CZ, DK, DM, DZ, EC, EE, EG, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GW, HR, HU, ID, IE, IL, IN, IS, IT, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MC, MD, MG, MK, ML, MN, MR, MW, MX, MZ, NA, NE, NI, NL, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SI, SK, SL, SN, SY, SZ, TD, TG, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, YU, ZA, ZM, ZW only).
TACKE, Michael [DE/DE]; (DE) (For US Only).
BERNDT, Peter [DE/CH]; (CH) (For US Only).
HAGMANN, Marie-Luise [DE/DE]; (DE) (For US Only).
KARL, Johann [DE/DE]; (DE) (For US Only).
LANGEN, Hanno [DE/DE]; (DE) (For US Only).
PALME, Stefan [DE/DE]; (DE) (For US Only).
ROESSLER, Markus [DE/DE]; (DE) (For US Only).
ROLLINGER, Wolfgang [DE/DE]; (DE) (For US Only).
ZOLG, Werner [DE/DE]; (DE) (For US Only)
Inventors: TACKE, Michael; (DE).
BERNDT, Peter; (CH).
HAGMANN, Marie-Luise; (DE).
KARL, Johann; (DE).
LANGEN, Hanno; (DE).
PALME, Stefan; (DE).
ROESSLER, Markus; (DE).
ROLLINGER, Wolfgang; (DE).
ZOLG, Werner; (DE)
Common
Representative:
ROCHE DIAGNOSTICS GMBH; NASER, Werner, Patent Department (TR-E), Postfach 11 52, 82372 Penzberg (DE)
Priority Data:
03015694.7 21.07.2003 EP
Title (EN) USE OF PROTEINS PROTEINASE 3 (PRN3) AND LEUKOCYTE ELASTASE INHIBITOR (ILEU) AS A MARKER FOR COLORECTAL CANCER
(FR) UTILISATION DE LA PROTEINASE 3(PRN3) ET DE L'INHIBITEUR DE L'ELASTASE LEUCOCYTAIRE (ILEU) EN TANT QUE MARQUEURS POUR LE CANCER COLORECTAL
Abstract: front page image
(EN)The present invention relates to the diagnosis of colorectal cancer. It discloses the use of PRN3/ILEU and/or unbound PRN3 in the diagnosis of colorectal cancer. It relates to a method for diagnosis of colorectal cancer from a stool sample, derived from an individual by measuring PRN3/ILEU and/or unbound PRN3 in said sample. Measurement of PRN3/ILEU and/or unbound PRN3 can, e.g., be used in the early detection or diagnosis of colorectal cancer.
(FR)L'invention concerne le diagnostic du cancer colorectal et, plus spécifiquement, l'utilisation de la protéine PRN3/ILEU et/ou PRN3 non liée dans le diagnostic du cancer colorectal. L'invention concerne également une méthode de diagnostic du cancer colorectal à partir d'un échantillon de selles prélevé chez un sujet. Cette méthode consiste à mesurer le taux de PRN3/ILEU et/ou de PRN3 non liée dans ledit échantillon. La mesure de PRN3/ILEU et/ou de PRN3 non liée peut, par exemple, être utile dans la détection ou le diagnostic précoces du cancer colorectal.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)