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1. (WO2005014649) METHOD FOR THE PREPARATION OF MOLECULES HAVING ANTIBODY ACTIVITY
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2005/014649 International Application No.: PCT/IB2004/002529
Publication Date: 17.02.2005 International Filing Date: 29.07.2004
Chapter 2 Demand Filed: 11.11.2004
IPC:
C07K 16/00 (2006.01) ,C07K 16/06 (2006.01) ,C07K 16/24 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
06
from serum
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
24
against cytokines, lymphokines or interferons
Applicants: BANERJEE, Amit[US/US]; US (UsOnly)
GUSTAFSON, Mark[US/US]; US (UsOnly)
HO, Sa, V.[US/US]; US (UsOnly)
MCLAUGHLIN, Joseph[US/US]; US (UsOnly)
THOMAS, Kristin[US/US]; US (UsOnly)
PHARMACIA CORPORATION[US/US]; 700 Chesterfield Parkway West Chesterfield, MO 63017-1732, US (AllExceptUS)
Inventors: BANERJEE, Amit; US
GUSTAFSON, Mark; US
HO, Sa, V.; US
MCLAUGHLIN, Joseph; US
THOMAS, Kristin; US
Agent: FULLER, Grover, F.; Pfizer Inc. P.O. Box 1027 St. Louis, MO 63006, US
Priority Data:
60/493,74008.08.2003US
Title (EN) METHOD FOR THE PREPARATION OF MOLECULES HAVING ANTIBODY ACTIVITY
(FR) METHODE DE PREPARATION DE MOLECULES AYANT UNE ACTIVITE D'ANTICORPS
Abstract:
(EN) The present invention provides a process for the preparation of an antibody, wherein the method comprises: fermenting a cell mixture comprising the cells and a supernatant solution, wherein the cells are capable of expressing the light chain and the heavy chain; separating the cells from the supernatant solution to form a cell pellet; allowing the cell pellet to stand for a hold time; and extracting the cell pellet with an extracting solution; thereby producing the antibody.
(FR) L'invention concerne une méthode de préparation d'anticorps. Selon cette méthode, on fermente un mélange de cellules qui comprend les cellules et une solution de surnageant, les cellules étant capables d'exprimer la chaîne légère et la chaîne lourde ; on sépare les cellules de la solution de surnageant afin de former une boulette constituée de cellules ; on laisse reposer la boulette de cellules pendant une période de séjour ; et on soumet la boulette de cellules à une extraction au moyen d'une solution d'extraction, de façon à produire les anticorps.
front page image
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)