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Machine translation
1. (WO2005014557) TETRAHYDROQUINAZOLINE DERIVATIVES AS CFR ANTAGONISTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/014557    International Application No.:    PCT/EP2004/008661
Publication Date: 17.02.2005 International Filing Date: 03.08.2004
Chapter 2 Demand Filed:    31.01.2005    
IPC:
C07D 239/94 (2006.01)
Applicants: F.HOFFMANN-LA ROCHE AG [CH/CH]; Grenzacherstrasse 124, CH-4070 Basel (CH) (For All Designated States Except US).
CLARK, Robin, Douglas [US/US]; (US) (For US Only).
COURNOYER, Richard, Leo [US/US]; (US) (For US Only).
O'YANG, Counde [US/US]; (US) (For US Only)
Inventors: CLARK, Robin, Douglas; (US).
COURNOYER, Richard, Leo; (US).
O'YANG, Counde; (US)
Agent: BRAUN Axel; Grenzacherstrasse 124, CH-4070 Basel (CH)
Priority Data:
60/494,511 12.08.2003 US
Title (EN) TETRAHYDROQUINAZOLINE DERIVATIVES AS CFR ANTAGONISTS
(FR) DERIVES DE LA TETRAHYDROQUINAZOLINE EN TANT QU'ANTAGONISTES CFR
Abstract: front page image
(EN)Compounds of the Formula (I): and pharmaceutically acceptable salts thereof, wherein m, R1, R2, R3 R4 and R6 are as defined herein. The invention also provides methods for preparing, compositions comprising the compounds of Formula (I), as well as their uses for the manufacture of medicaments useful in the treatment of diseases such as phobias, stress-related illnesses, mood disorders, eating disorders, generalized anxiety disorders, stress-induced gastrointestinal dysfunctions, neurodegenerative diseases, and neuropsychiatric disorders.
(FR)L'invention concerne des composés de formule (I) et des sels correspondants acceptables pharmaceutiquement, m, R1, R2, R3, R4 et R6 y étant définis tels que mentionnés. Cette invention a aussi trait à des procédés de préparation de compositions contenant les composés de formule (I), ainsi qu'à leurs utilisations dans l'élaboration de médicaments utilisés dans le traitement de maladies, telles que les phobies, les troubles liés au stress, les troubles de l'humeur, les troubles de l'alimentation, les troubles d'anxiété généralisés, les dysfonctionnements gastro-intestinaux induits par le stress, les maladies neurodégénératives et les troubles neuropsychiatriques.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)