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1. (WO2005014552) QUINOLINE AND QUINAZOLINE DERIVATIVES HAVING AFFINITY FOR 5HT1-TYPE RECEPTORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/014552    International Application No.:    PCT/EP2004/008000
Publication Date: 17.02.2005 International Filing Date: 15.07.2004
IPC:
C07D 215/38 (2006.01), C07D 401/12 (2006.01), C07D 405/12 (2006.01), C07D 409/12 (2006.01), C07D 413/12 (2006.01), C07D 417/12 (2006.01)
Applicants: GLAXO GROUP LIMITED [GB/GB]; Glaxo Wellcome House, Berkeley Avenue, Greenford Middlesex UB6 0NN (GB) (For All Designated States Except US).
BERGAUER, Markus [DE/IT]; (IT) (For US Only).
BERTANI, Barbara [IT/IT]; (IT) (For US Only).
BIAGETTI, Matteo [IT/IT]; (IT) (For US Only).
BROMIDGE, Steven Mark [GB/IT]; (IT) (For US Only).
FALCHI, Alessandro [IT/IT]; (IT) (For US Only).
LESLIE, Colin Philip [GB/IT]; (IT) (For US Only).
MERLO, Giancarlo [IT/IT]; (IT) (For US Only).
PIZZI, Domenica Antonia [IT/IT]; (IT) (For US Only).
RINALDI, Marilisa [IT/IT]; (IT) (For US Only).
STASI, Luigi Piero [IT/IT]; (IT) (For US Only).
TIBASCO, Jessica [IT/IT]; (IT) (For US Only).
VONG, Antonio, Kuok, Keong [GB/GB]; (GB) (For US Only).
WARD, Simon, Edward [GB/GB]; (GB) (For US Only)
Inventors: BERGAUER, Markus; (IT).
BERTANI, Barbara; (IT).
BIAGETTI, Matteo; (IT).
BROMIDGE, Steven Mark; (IT).
FALCHI, Alessandro; (IT).
LESLIE, Colin Philip; (IT).
MERLO, Giancarlo; (IT).
PIZZI, Domenica Antonia; (IT).
RINALDI, Marilisa; (IT).
STASI, Luigi Piero; (IT).
TIBASCO, Jessica; (IT).
VONG, Antonio, Kuok, Keong; (GB).
WARD, Simon, Edward; (GB)
Agent: KONDO, Rie; GlaxoSmithKline, Corporate Intellectual Property (CN925.1), 980 Great West Road, Brentford Middlesex TW8 9GS (GB)
Priority Data:
0316915.8 18.07.2003 GB
Title (EN) QUINOLINE AND QUINAZOLINE DERIVATIVES HAVING AFFINITY FOR 5HT1-TYPE RECEPTORS
(FR) DERIVES DE QUINOLINE ET DE QUINAZOLINE PRESENTANT UNE AFFINITE VIS-A-VIS DES RECEPTEURS DU TYPE 5HT1
Abstract: front page image
(EN)Compounds of formula (I) and pharmaceutically acceptable salts thereof are provided: wherein R1, m, X, R2, n, W, p, Y, Z, R3, R4, R5 and q have the meanings as defined in the description. Methods of preparation and uses thereof in therapy, particularly for CNS disorders such as depression or anxiety, are also disclosed.
(FR)L'invention concerne des composés correspondant à la formule (I) et des sels pharmaceutiquement acceptables de ceux-ci. Dans ladite formule (I), R1, m, X, R2, n, W, p, Y, Z, R3, R4, R5 et q correspondent aux définitions données dans la description. L'invention concerne également des procédés de préparation et les utilisations de ces composés en thérapie, en particulier pour le traitement de troubles du système nerveux central tels que la dépression ou l'anxiété.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)