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1. (WO2005013931) USE OF HALOGENATED HYDROXYDIPHENYL ETHER COMPOUNDS FOR THE TREATMENT OF THE SKIN
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/013931    International Application No.:    PCT/EP2004/051379
Publication Date: 17.02.2005 International Filing Date: 07.07.2004
IPC:
A61K 8/34 (2006.01), A61Q 19/02 (2006.01)
Applicants: CIBA SPECIALTY CHEMICALS HOLDING INC. [CH/CH]; Klybeckstrasse 141, CH-4057 Basel (CH) (For All Designated States Except US).
BASCHONG, Werner [CH/CH]; (CH) (For US Only).
SCHNYDER, Marcel [CH/CH]; (CH) (For US Only)
Inventors: BASCHONG, Werner; (CH).
SCHNYDER, Marcel; (CH)
Common
Representative:
CIBA SPECIALTY CHEMICALS HOLDING INC.; Patent Department, Klybeckstrasse 141, CH-4057 Basel (CH)
Priority Data:
03405542.6 16.07.2003 EP
Title (EN) USE OF HALOGENATED HYDROXYDIPHENYL ETHER COMPOUNDS FOR THE TREATMENT OF THE SKIN
(FR) UTILISATION DE COMPOSES D'ETHER D'HYDROXYDIPHENYLE HALOGENES POUR LE TRAITEMENT DE LA PEAU
Abstract: front page image
(EN)The use of hydroxydiphenyl ether compounds of formula (I), wherein R1, R2 and R3 are each independently of the others hydrogen; hydroxy; C1-C20alkyl; hydroxy-substituted C1-C20alkyl; C5-C7cycloalkyl; C1-C20alkoxy; C1-C6alkylcarbonyl; phenyl; or phenyl-C1-C3alkyl; R4 is hydrogen, C1-C20alkyl; hydroxy-substituted C1-C20alkyl; C5-C7cycloalkyl; hydroxy; formyl; acetonyl; allyl; carboxy; carboxy-C1-C3alkyl; carboxyallyl; C2-C20alkenyl; C1-C6alkylcarbonyl; C1-C3alkylcarbonyl-C1-C3alkyl; phenyl; or phenyl-C1-C3alkyl; and R5 is hydrogen; C1-C20alkoxy; or C1-C6alkylcarbonyl; as melanogenesis inhibitors and for lightening the skin.
(FR)La présente invention a trait à l'utilisation de composés d'éther d'hydroxydiphényle de formule (I), dans laquelle : R1, R2 et R3 sont chacun indépendamment des autres hydrogène; hydroxy; alkyle en C1-C20; alkyle en C1-C20 à substitution hydroxy; cycloalkyle en C5-C7; alcoxy en C1-C20; alkylcarbonyle en C1-C6; phényle; ou phényle- alkyle en C1-C3; R4 est hydrogène, alkyle en C1-C20; alkyle en C1-C20 à substitution hydroxy; cycloalkyle en C5-C7; hydroxy; formyle; acétonyle; allyle; carboxy; carboxy-alkyle en C1-C3; carboxyallyle; alcényle en C2-C20; alkylcarbonyle en C1-C6; alkylcarbonyle en C1-C3 alkyle en C1-C3; phényle; ou phényle- alkyle en C1-C3; et R5 est hydrogène; alcoxy en C1-C20; ou alkylcarbonyle en C1-C6 ; en tant qu'inhibiteurs de la mélanogenèse et pour l'éclaircissement de la peau.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)