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1. (WO2005012907) SYSTEMS AND METHODS FOR CHARACTERIZING KIDNEY DISEASES

Pub. No.:    WO/2005/012907    International Application No.:    PCT/US2004/024703
Publication Date: Fri Feb 11 00:59:59 CET 2005 International Filing Date: Sat Jul 31 01:59:59 CEST 2004
IPC: G01N 33/68
Applicants: RENOVAR, INC.
HUAIZHONG HU
KNECHTLE, Stuart
Inventors: HUAIZHONG HU
KNECHTLE, Stuart
Title: SYSTEMS AND METHODS FOR CHARACTERIZING KIDNEY DISEASES
Abstract:
The present invention relates to methods of diagnosing, predicting and monitoring kidney diseases, including acute renal failure, renal tubular interstitial disease and glomerulonephritis. In particular, the present invention relates to the detection, prediction and monitoring of kidney diseases by detection of CXCR3 and CCL chemokines in urine. The present invention further relates to methods and compositions for assessing the efficacy of agents and interventions used to treat kidney diseases. Figure (1) shows the design of the Beads FACS method for quantification of chemokines IP-10, Mig, and I-TAC used in some embodiments of the present invention.