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1. (WO2005012322) PROCESS FOR PRODUCING ERYTHROMYCIN A 11,12-CYCLIC CARBONATE
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2005/012322 International Application No.: PCT/JP2004/011150
Publication Date: 10.02.2005 International Filing Date: 04.08.2004
IPC:
C07H 17/08 (2006.01)
Applicants: KASHIMURA, Masato[JP/JP]; JP (UsOnly)
KAMIYAMA, Hiroaki[JP/JP]; JP (UsOnly)
ADACHI, Takashi[JP/JP]; JP (UsOnly)
TAISHO PHARMACEUTICAL CO., LTD.[JP/JP]; 24-1, Takada 3-chome Toshima-ku, Tokyo 1708633, JP (AllExceptUS)
Inventors: KASHIMURA, Masato; JP
KAMIYAMA, Hiroaki; JP
ADACHI, Takashi; JP
Agent: TAKAGI, Chiyoshi; Subaru Patent Office Kojimachi Koyo Bldg. 1-10, Kojimachi Chiyoda-ku, Tokyo 1020083, JP
Priority Data:
2003-20608905.08.2003JP
Title (EN) PROCESS FOR PRODUCING ERYTHROMYCIN A 11,12-CYCLIC CARBONATE
(FR) PROCEDE DE PRODUCTION CARBONATE 11,12-CYCLIQUE D'ERYTHROMYCINE A
(JA) エリスロマイシンA 11,12−サイクリックカーボネートの製造方法
Abstract: front page image
(EN) A process for producing erythromycin A 11,12-cyclic carbonate (compound (II)) from erythromycin A (compound (I)), which is shown by the reaction scheme, [Chemical formula 1] (I) → (II) the process comprising reacting erythromycin A with ethylene carbonate and cesium carbonate in one or more solvents selected among diethyl ether, diisopropyl ether, and t-butyl methyl ether. Thus, erythromycin A 11,12-cyclic carbonate is effectively produced.
(FR) L'invention concerne un procédé de production de carbonate 11,12-cyclique d'érythromycine A (composé (II)) à partir d'érythromycine A (composé (I)), représenté par le schéma réactionnel (formule chimique 1), (I) -> (II). Ce procédé consiste à faire réagir l'érythromycine A avec du carbonate d'éthylène et du carbonate de césium dans au moins un solvant sélectionné parmi l'éther diétylique, l'éther ddisopropylique et l'éther t-butylméthylique. Cela permet d'obtenir le carbonate 11,12-cyclique d'érythromycine A.
(JA) not available
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)