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1. (WO2005011686) 2-IMINO-4-(THIO) OXO-5-POLY CYCLOVINYLAZOLINES FOR USE AS P13 KINASE IHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/011686    International Application No.:    PCT/EP2004/051625
Publication Date: 10.02.2005 International Filing Date: 27.07.2004
Chapter 2 Demand Filed:    04.04.2005    
IPC:
C07D 417/06 (2006.01), C07D 417/14 (2006.01)
Applicants: Applied Research Systems ARS Holding N.V. [NL/NL]; Pietermaai 15, Curacao (NL) (For All Designated States Except US).
RUECKLE, Thomas [DE/CH]; (CH) (For US Only).
SHAW, Jeffrey [IT/CH]; (CH) (For US Only).
CHURCH, Dennis [US/CH]; (CH) (For US Only).
COVINI, David [CH/FR]; (FR) (For US Only)
Inventors: RUECKLE, Thomas; (CH).
SHAW, Jeffrey; (CH).
CHURCH, Dennis; (CH).
COVINI, David; (FR)
Agent: HASSA, Juergen; Serono International SA, Intellectual Property Department, 12, Chemin des Aulx, CH-1228 Plan-les-Ouates (CH)
Priority Data:
03102313.8 28.07.2003 EP
Title (EN) 2-IMINO-4-(THIO) OXO-5-POLY CYCLOVINYLAZOLINES FOR USE AS P13 KINASE IHIBITORS
(FR) 2-IMINO-4-(THIO) OXO-5-POLY CYCLOVINYLAZOLINES UTILISES COMME INHIBITEURS DE P13 KINASE
Abstract: front page image
(EN)The present invention is related to 2-imino-azolinone-vinyl fused-benzene derivatives of Formula (1) in particular for the treatment and/or prophylaxis of autoimmune disorders and/or inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, kidney diseases, platelet aggregation, cancer, transplantation, graft rejection or lung injuries.
(FR)L'invention concerne des dérivés benzéniques condensés au 2-imino-azolinone-vinyle, de formule (I), en particulier pour le traitement et/ou la prophylaxie d'affections auto-immunes et/ou de maladies inflammatoires, de maladies cardiovasculaires, de maladies neurodégénératives, de maladies rénales, de cas d'agrégation plaquettaire, de cancer, transplantation, rejet de greffe ou de troubles pulmonaires.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)