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Machine translation
1. (WO2005010154) 7 AND 8 MEMBERED HETEROCYCLIC CYCLOPENTYL BENZYLAMIDE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/010154    International Application No.:    PCT/US2004/021996
Publication Date: 03.02.2005 International Filing Date: 09.07.2004
IPC:
A61K 31/425 (2006.01), A61K 31/55 (2006.01), A61P 19/00 (2006.01), A61P 29/00 (2006.01), A61P 31/00 (2006.01), C07D 417/08 (2006.01)
Applicants: MERCK & CO., INC. [US/US]; 126 East Lincoln Avenue, Rahway, New Jersey 07065-0907 (US) (For All Designated States Except US).
GE, Min [CN/US]; (US) (For US Only).
GOBLE, Stephen, D. [US/US]; (US) (For US Only).
PASTERNAK, Alexander [US/US]; (US) (For US Only).
YANG, Lihu [US/US]; (US) (For US Only)
Inventors: GE, Min; (US).
GOBLE, Stephen, D.; (US).
PASTERNAK, Alexander; (US).
YANG, Lihu; (US)
Common
Representative:
MERCK & CO., INC.; 126 East Lincoln Avenue, Rahway, NJ 07065-0907 (US)
Priority Data:
60/487,317 15.07.2003 US
Title (EN) 7 AND 8 MEMBERED HETEROCYCLIC CYCLOPENTYL BENZYLAMIDE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY
(FR) MODULATEURS BENZYLAMIDES DE CYCLOPENTYLE HETEROCYCLIQUES A 7 ET 8 ELEMENTS, UTILES POUR MODULER L'ACTIVITE DES RECEPTEURS DE CHIMIOKINES
Abstract: front page image
(EN)The present invention is directed to compounds of the formula: wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 and R16 are as defined herein which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptor CCR-2.
(FR)La présente invention se rapporte à des composés représentés par la formule (I), dans laquelle R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 et R16 sont définis dans la description. Ces composés sont utiles en tant que modulateurs de l'activité des récepteurs de chimiokines. En particulier, ces composés sont utiles en tant que modulateurs du récepteur de chimiokines CCR-2.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)